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gltI glutamate/aspartate ABC transporter periplasmic binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946938, updated on 4-Apr-2024

Summary

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Gene symbol
gltI
Gene description
glutamate/aspartate ABC transporter periplasmic binding protein
Primary source
ASAP:ABE-0002241
Locus tag
b0655
See related
ECOCYC:G6359
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0648; ybeJ; yzzK
Summary
GltI is the periplasmic binding component of the glutamate ABC transporter. [More information is available at EcoCyc: G6359].
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Genomic context

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Sequence:
NC_000913.3 (686839..687747, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene glutamate/aspartate ABC transporter ATP binding subunit Neighboring gene glutamate/aspartate ABC transporter membrane subunit GltK Neighboring gene glutamate/aspartate ABC transporter membrane subunit GltJ Neighboring gene ncRNA Neighboring gene IS5 family transposase and trans-activator Neighboring gene apolipoprotein N-acyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure of a glutamate/aspartate binding protein complexed with a glutamate molecule: structural basis of ligand specificity at atomic resolution. Hu Y, et al. J Mol Biol, 2008 Sep 26. PMID 18640128
  2. A periplasmic glutamate/aspartate binding protein from Shigella flexneri: Gene cloning, over-expression, purification and preliminary crystallographic studies of the recombinant protein. Fan CP, et al. Protein Pept Lett, 2006. PMID 16800808
  3. Interactions of a glutamate-aspartate binding protein with the glutamate transport system of Escherichia coli. Willis RC, et al. J Biol Chem, 1975 Apr 10. PMID 1091636
  4. Purification and properties of a periplasmic glutamate-aspartate binding protein from Escherichia coli K12 strain W3092. Willis RC, et al. J Biol Chem, 1975 Apr 10. PMID 1091635
  5. Purification and properties of glutamate binding protein from the periplasmic space of Escherichia coli K-12. Barash H, et al. Biochim Biophys Acta, 1975 Mar 28. PMID 236016

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: The gcvB gene encodes a small untranslated RNA involved in expression of the dipeptide and oligopeptide transport systems in Escherichia coli.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables aspartate binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables glutamate binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-aspartate import across plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within L-aspartate transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in L-glutamate import across plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within L-glutamate transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in outer membrane-bounded periplasmic space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
 PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glutamate/aspartate ABC transporter periplasmic binding protein
NP_415188.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    686839..687747 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415188.1 glutamate/aspartate ABC transporter periplasmic binding protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415188.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8H9XK75
    Conserved Domains (1) summary
    PRK10797
    Location:1 → 302
    PRK10797; glutamate and aspartate transporter subunit; Provisional
Nucleotide Protein
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