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hyfH hydrogenase 4 component H [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 946965, updated on 11-Apr-2024

Summary

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Gene symbol
hyfH
Gene description
hydrogenase 4 component H
Primary source
ASAP:ABE-0008196
Locus tag
b2488
See related
ECOCYC:G7305
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2484
Summary
This subunit contains two 4Fe-4S and one Fe-S clusters. [More information is available at EcoCyc: G7305].
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Genomic context

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Sequence:
NC_000913.3 (2610164..2610709)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene hydrogenase 4 component E Neighboring gene hydrogenase 4 component F Neighboring gene hydrogenase 4 catalytic subunit HyfG Neighboring gene hydrogenase 4 catalytic subunit HyfI Neighboring gene putative hydrogenase 4 assembly protein Neighboring gene DNA-binding transcriptional activator HyfR

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Participation of hyf-encoded hydrogenase 4 in molecular hydrogen release coupled with proton-potassium exchange in Escherichia coli. Bagramyan K, et al. Membr Cell Biol, 2001. PMID 11817571
  2. Phosphorylation of ribosomal proteins in HeLa cells infected with vaccinia virus. Kaerlein M, et al. Nature, 1976 Jan 15. PMID 1246353
  3. Expression and regulation of a silent operon, hyf, coding for hydrogenase 4 isoenzyme in Escherichia coli. Self WT, et al. J Bacteriol, 2004 Jan. PMID 14702328, Free PMC Article
  4. A 12-cistron Escherichia coli operon (hyf) encoding a putative proton-translocating formate hydrogenlyase system. Andrews SC, et al. Microbiology (Reading), 1997 Nov. PMID 9387241
  5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables 4 iron, 4 sulfur cluster binding ISM
Inferred from Sequence Model
more info
 PubMed 
contributes_to NADH dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on NAD(P)H IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in aerobic respiration IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of [Ni-Fe] hydrogenase complex RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
hydrogenase 4 component H

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2610164..2610709
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416983.1 hydrogenase 4 component H [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_416983.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A827Y215
    Conserved Domains (1) summary
    PRK08222
    Location:1 → 181
    PRK08222; hydrogenase 4 subunit H; Validated
Nucleotide Protein
Heading Accession and Version

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