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hycF formate hydrogenlyase subunit HycF [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947048, updated on 11-Apr-2024

Summary

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Gene symbol
hycF
Gene description
formate hydrogenlyase subunit HycF
Primary source
ASAP:ABE-0008942
Locus tag
b2720
See related
ECOCYC:EG10479
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2715; hevF
Summary
FhlA regulon. [More information is available at EcoGene: EG10479]. HycF is thought to encode a 4Fe-4S ferredoxin type protein, an intermediate electron carrier protein . [More information is available at EcoCyc: EG10479].
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Genomic context

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Sequence:
NC_000913.3 (2844210..2844752, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene 6-phospho-beta-glucosidase AscB Neighboring gene hydrogenase 3 maturation protease Neighboring gene formate hydrogenlyase assembly protein Neighboring gene formate hydrogenlyase subunit HycG Neighboring gene formate hydrogenlyase subunit HycE Neighboring gene formate hydrogenlyase subunit HycD

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Microbial reduction of technetium by Escherichia coli and Desulfovibrio desulfuricans: enhancement via the use of high-activity strains and effect of process parameters. Lloyd JR, et al. Biotechnol Bioeng, 1999. PMID 10567070
  2. Reduction and removal of heptavalent technetium from solution by Escherichia coli. Lloyd JR, et al. J Bacteriol, 1997 Mar. PMID 9068649, Free PMC Article
  3. Regulation of gene expression in fermentative and respiratory systems in Escherichia coli and related bacteria. Lin EC, et al. Annu Rev Genet, 1991. PMID 1812811
  4. Regulated expression in vitro of genes coding for formate hydrogenlyase components of Escherichia coli. Hopper S, et al. J Biol Chem, 1994 Jul 29. PMID 8034728
  5. The hydrogenases and formate dehydrogenases of Escherichia coli. Sawers G. Antonie Van Leeuwenhoek, 1994. PMID 7747941

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables 4 iron, 4 sulfur cluster binding RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
contributes_to NADH dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on NAD(P)H IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in aerobic respiration IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in anaerobic electron transport chain IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in anaerobic respiration IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in formate oxidation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in glucose catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of formate dehydrogenase complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
formate hydrogenlyase subunit HycF
NP_417200.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2844210..2844752 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417200.1 formate hydrogenlyase subunit HycF [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417200.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6L7CE10, A0AA87HR18
    Conserved Domains (1) summary
    PRK12387
    Location:1 → 180
    PRK12387; formate hydrogenlyase complex iron-sulfur subunit; Provisional
Nucleotide Protein
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