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xdhA putative xanthine dehydrogenase molybdenum-binding subunit XdhA [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947116, updated on 4-Feb-2024

Summary

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Gene symbol
xdhA
Gene description
putative xanthine dehydrogenase molybdenum-binding subunit XdhA
Primary source
ASAP:ABE-0009413
Locus tag
b2866
See related
ECOCYC:G7485
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2862; ygeS
Summary
AFMB Structural Genomics target Number 102 (http://afmb.cnrs-mrs.fr/article171.html). [More information is available at EcoGene: EG13049]. XdhA has similarity to the molybdenum cofactor-containing domains of Drosophila melanogaster xanthine dehydrogenase and Desulfovibrio gigas aldehyde oxidoreductase . [More information is available at EcoCyc: G7485].
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Genomic context

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Sequence:
NC_000913.3 (3000345..3002603)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Gly Neighboring gene amidase activator Neighboring gene putative xanthine dehydrogenase FAD-binding subunit XdhB Neighboring gene putative xanthine dehydrogenase iron-sulfur-binding subunit XdhC Neighboring gene putative sigma(54)-dependent transcriptional regulator YgeV

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molybdenum enzymes, their maturation and molybdenum cofactor biosynthesis in Escherichia coli. Iobbi-Nivol C, et al. Biochim Biophys Acta, 2013 Aug-Sep. PMID 23201473
  2. Molybdenum cofactor-dependent resistance to N-hydroxylated base analogs in Escherichia coli is independent of MobA function. Kozmin SG, et al. Mutat Res, 2007 Jun 1. PMID 17349664, Free PMC Article
  3. Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage. Xi H, et al. J Bacteriol, 2000 Oct. PMID 10986234, Free PMC Article
  4. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article
  5. Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Hayashi K, et al. Mol Syst Biol, 2006. PMID 16738553, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables xanthine dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in hypoxanthine catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in hypoxanthine catabolic process NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in purine nucleobase metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in purine ribonucleoside salvage IEA
Inferred from Electronic Annotation
more info
  
involved_in purine ribonucleoside salvage NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm NAS
Non-traceable Author Statement
more info
 PubMed 
part_of xanthine dehydrogenase complex NAS
Non-traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
putative xanthine dehydrogenase molybdenum-binding subunit XdhA
NP_417342.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3000345..3002603
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417342.1 putative xanthine dehydrogenase molybdenum-binding subunit XdhA [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417342.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    B7MM53, C3SW79, C3SW80
    Conserved Domains (1) summary
    PRK09970
    Location:1 → 752
    PRK09970; xanthine dehydrogenase subunit XdhA; Provisional
Nucleotide Protein
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