msrB methionine sulfoxide reductase B [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Gene symbol: msrB
Gene description: methionine sulfoxide reductase B
Primary source: ASAP:ABE-0005916
Locus tag: b1778
See related: ECOCYC:EG12394
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK1776; yeaA
Summary: Tightly binds zinc/iron. [More information is available at EcoGene: EG12394]. MsrB exhibits methionine sulfoxide reductase activity (Km of 6.7 mM) and dimethylsulfoxide reductase activity in vitro . [More information is available at EcoCyc: EG12394].
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NC_000913.3 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables L-methionine-(R)-S-oxide reductase activity	IDA Inferred from Direct Assay more info	PubMed
enables iron ion binding	IDA Inferred from Direct Assay more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	IEA Inferred from Electronic Annotation more info
enables peptide-methionine (R)-S-oxide reductase activity	IBA Inferred from Biological aspect of Ancestor more info
enables peptide-methionine (R)-S-oxide reductase activity	IDA Inferred from Direct Assay more info	PubMed
enables peptide-methionine (R)-S-oxide reductase activity	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IDA Inferred from Direct Assay more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein repair	IDA Inferred from Direct Assay more info	PubMed
involved_in protein repair	IEA Inferred from Electronic Annotation more info
involved_in protein repair	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within response to cadmium ion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in response to oxidative stress	IEA Inferred from Electronic Annotation more info
involved_in response to oxidative stress	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed

NP_416292.1

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The following sections contain reference sequences that belong to a specific genome build. Explain