hyfD hydrogenase 4 component D [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Gene symbol: hyfD
Gene description: hydrogenase 4 component D
Primary source: ASAP:ABE-0008185
Locus tag: b2484
See related: ECOCYC:G7301
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK2480
Summary: On the basis of sequence similarity to hycBCDEFG, which encodes hydrogenase 3, the ten-gene cluster hyfABCDEFGHIJ was presumed to encode a hydrogenase that interacts with formate dehydrogenase (FdhF) to produce an active formate hydrogenlyase complex. [More information is available at EcoCyc: G7301].
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NC_000913.3 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables NADH dehydrogenase (ubiquinone) activity	IEA Inferred from Electronic Annotation more info
enables NADH dehydrogenase activity	IBA Inferred from Biological aspect of Ancestor more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in ATP synthesis coupled electron transport	IEA Inferred from Electronic Annotation more info
involved_in anaerobic electron transport chain	NAS Non-traceable Author Statement more info	PubMed
involved_in anaerobic respiration	NAS Non-traceable Author Statement more info	PubMed
involved_in electron transport coupled proton transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in formate oxidation	NAS Non-traceable Author Statement more info	PubMed
involved_in glucose catabolic process	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
part_of [Ni-Fe] hydrogenase complex	RCA inferred from Reviewed Computational Analysis more info	PubMed
part_of formate dehydrogenase complex	NAS Non-traceable Author Statement more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	NAS Non-traceable Author Statement more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISM Inferred from Sequence Model more info	PubMed

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