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kduD putative 2-keto-3-deoxy-D-gluconate dehydrogenase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947323, updated on 4-Apr-2024

Summary

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Gene symbol
kduD
Gene description
putative 2-keto-3-deoxy-D-gluconate dehydrogenase
Primary source
ASAP:ABE-0009330
Locus tag
b2842
See related
ECOCYC:EG12361
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2840; ygeC; yqeD
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Genomic context

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Sequence:
NC_000913.3 (2982497..2983258, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional dual regulator LysR Neighboring gene amino acid racemase YgeA Neighboring gene arabinose:H(+) symporter Neighboring gene 5-dehydro-4-deoxy-D-glucuronate isomerase Neighboring gene putative acyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Selection of thiol- and disulfide-containing proteins of Escherichia coli on activated thiol-Sepharose. Hu W, et al. Anal Biochem, 2010 Mar 15. PMID 19903445
  2. Biocatalytic synthesis of 4-pregnen-20,21-diol-3-one, a selective inhibitor of human 5alpha-reductase type II. Hannemann F, et al. J Enzyme Inhib Med Chem, 2007 Oct. PMID 18035825
  3. Novel insights into E. coli's hexuronate metabolism: KduI facilitates the conversion of galacturonate and glucuronate under osmotic stress conditions. Rothe M, et al. PLoS One, 2013. PMID 23437267, Free PMC Article
  4. The cloning, DNA sequence, and overexpression of the gene araE coding for arabinose-proton symport in Escherichia coli K12. Maiden MC, et al. J Biol Chem, 1988 Jun 15. PMID 2836407
  5. Comparative genomics of the KdgR regulon in Erwinia chrysanthemi 3937 and other gamma-proteobacteria. Rodionov DA, et al. Microbiology (Reading), 2004 Nov. PMID 15528647

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. KduD encodes an oxidoreductase that converts both sugar and steroid substrates.
    Title: Escherichia coli kduD encodes an oxidoreductase that converts both sugar and steroid substrates.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 11-deoxycorticosterone reductase activity IEA
Inferred from Electronic Annotation
more info
  
enables 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
enables 2-deoxy-D-gluconate 3-dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
enables NAD binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IDA
Inferred from Direct Assay
more info
 PubMed 
enables steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within D-galacturonate catabolic process IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within D-glucuronate catabolic process IEP
Inferred from Expression Pattern
more info
 PubMed 

General protein information

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Preferred Names
putative 2-keto-3-deoxy-D-gluconate dehydrogenase
NP_417319.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2982497..2983258 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417319.1 putative 2-keto-3-deoxy-D-gluconate dehydrogenase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417319.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9AQ27
    Conserved Domains (1) summary
    PRK08993
    Location:1 → 253
    PRK08993; 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD
Nucleotide Protein
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