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glcD glycolate dehydrogenase, putative FAD-linked subunit [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947353, updated on 27-Nov-2023

Summary

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Gene symbol
glcD
Gene description
glycolate dehydrogenase, putative FAD-linked subunit
Primary source
ASAP:ABE-0009773
Locus tag
b2979
See related
ECOCYC:G7545
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2974; gox; yghM
Summary
Glycolate oxidase catalyzes the first step in the utilization of glycolate as the sole source of carbon . [More information is available at EcoCyc: G7545].
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Genomic context

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Sequence:
NC_000913.3 (3126522..3128021, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene glycolate dehydrogenase, putative iron-sulfur subunit Neighboring gene glycolate dehydrogenase, putative FAD-binding subunit Neighboring gene DNA-binding transcriptional dual regulator GlcC Neighboring gene putative DNA-binding transcriptional regulator YghO Neighboring gene IS5 family transposase and trans-activator

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Glycolate oxidoreductase in Escherichia coli. Lord JM. Biochim Biophys Acta, 1972 May 25. PMID 4557653
  2. The intracellular localization of glycolate oxidoreductase in Escherichia coli. Sallal AK, et al. FEBS Lett, 1989 Dec 4. PMID 2689218
  3. The gene yghK linked to the glc operon of Escherichia coli encodes a permease for glycolate that is structurally and functionally similar to L-lactate permease. Núñez MF, et al. Microbiology (Reading), 2001 Apr. PMID 11283302
  4. Cross-induction of glc and ace operons of Escherichia coli attributable to pathway intersection. Characterization of the glc promoter. Pellicer MT, et al. J Biol Chem, 1999 Jan 15. PMID 9880556
  5. Over 1000 genes are involved in the DNA damage response of Escherichia coli. Khil PP, et al. Mol Microbiol, 2002 Apr. PMID 11967071

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables (S)-2-hydroxy-acid oxidase activity IEA
Inferred from Electronic Annotation
more info
  
enables D-2-hydroxy-acid dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
enables FAD binding IEA
Inferred from Electronic Annotation
more info
  
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables glycolate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycolate dehydrogenase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within glycolate catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of glycolate oxidase complex IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glycolate dehydrogenase, putative FAD-linked subunit
NP_417453.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3126522..3128021 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417453.1 glycolate dehydrogenase, putative FAD-linked subunit [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417453.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9AD80
    Conserved Domains (1) summary
    PRK11230
    Location:1 → 499
    PRK11230; glycolate oxidase subunit GlcD; Provisional
Nucleotide Protein
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