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dtpD dipeptide:H(+) symporter DtpD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947368, updated on 4-Apr-2024

Summary

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Gene symbol
dtpD
Gene description
dipeptide:H(+) symporter DtpD
Primary source
ASAP:ABE-0002420
Locus tag
b0709
See related
ECOCYC:G6378
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0698; ybgH
Summary
Major Facilitator Superfamily (MFS). [More information is available at EcoGene: EG13304]. The YbgH protein is an uncharacterised member of the POT family of peptide transporters . [More information is available at EcoCyc: G6378].
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Genomic context

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Sequence:
NC_000913.3 (741075..742556, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene H repeat-associated putative transposase YbfD Neighboring gene DUF1722 domain-containing protein YbgA Neighboring gene deoxyribodipyrimidine photolyase Neighboring gene radiation resistance protein YbgI Neighboring gene 5-oxoprolinase component B Neighboring gene 5-oxoprolinase component C

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure of the E. coli peptide transporter YbgH. Zhao Y, et al. Structure, 2014 Aug 5. PMID 25066136
  2. DtpB (YhiP) and DtpA (TppB, YdgR) are prototypical proton-dependent peptide transporters of Escherichia coli. Harder D, et al. FEBS J, 2008 Jul. PMID 18485005
  3. Projection structure of DtpD (YbgH), a prokaryotic member of the peptide transporter family. Casagrande F, et al. J Mol Biol, 2009 Dec 11. PMID 19782088
  4. The POT family of transport proteins. Paulsen IT, et al. Trends Biochem Sci, 1994 Oct. PMID 7817396
  5. Microbial drug efflux proteins of the major facilitator superfamily. Saidijam M, et al. Curr Drug Targets, 2006 Jul. PMID 16842212

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables dipeptide transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables dipeptide transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables dipeptide transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables peptide transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables peptide:proton symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables peptide:proton symporter activity IEA
Inferred from Electronic Annotation
more info
  
enables peptide:proton symporter activity RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables tripeptide transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in dipeptide transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within dipeptide transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in dipeptide transport IEA
Inferred from Electronic Annotation
more info
  
involved_in oligopeptide transport IEA
Inferred from Electronic Annotation
more info
  
involved_in peptide transport IEA
Inferred from Electronic Annotation
more info
  
involved_in protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in tripeptide transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
dipeptide:H(+) symporter DtpD

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    741075..742556 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415237.1 dipeptide:H(+) symporter DtpD [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415237.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A827QTX6, A0AA87ELM4
    Conserved Domains (1) summary
    PRK15462
    Location:1 → 493
    PRK15462; dipeptide permease
Nucleotide Protein
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