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ubiI 2-octaprenylphenol 6-hydroxylase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947389, updated on 23-Nov-2023

Summary

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Gene symbol
ubiI
Gene description
2-octaprenylphenol 6-hydroxylase
Primary source
ASAP:ABE-0009543
Locus tag
b2906
See related
ECOCYC:EG11333
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2901; visC
Summary
A deletion of visC has no effect on photosensitivity or aerobic respiration (Nakahigashi, 1992). visC, ubiH, ubiF and mhpA are paralogs. [More information is available at EcoGene: EG11333]. Deletion of visC has no effect on photosensitivity or aerobic respiration . [More information is available at EcoCyc: EG11333].
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Genomic context

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Sequence:
NC_000913.3 (3051115..3052317, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene aminomethyltransferase Neighboring gene protein YqfI Neighboring gene 2-octaprenyl-6-methoxyphenol 4-hydroxylase Neighboring gene Xaa-Pro aminopeptidase Neighboring gene PF03695 family protein YgfB

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ubiI, a new gene in Escherichia coli coenzyme Q biosynthesis, is involved in aerobic C5-hydroxylation. Hajj Chehade M, et al. J Biol Chem, 2013 Jul 5. PMID 23709220, Free PMC Article
  2. Isolation and characterization of a light-sensitive mutant of Escherichia coli K-12 with a mutation in a gene that is required for the biosynthesis of ubiquinone. Nakahigashi K, et al. J Bacteriol, 1992 Nov. PMID 1339425, Free PMC Article
  3. A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone. Hajj Chehade M, et al. Cell Chem Biol, 2019 Apr 18. PMID 30686758
  4. Prediction of lipoprotein signal peptides in Gram-negative bacteria. Juncker AS, et al. Protein Sci, 2003 Aug. PMID 12876315, Free PMC Article
  5. Fine-tuning the prediction of sequences cleaved by signal peptidase II: a curated set of proven and predicted lipoproteins of Escherichia coli K-12. Gonnet P, et al. Proteomics, 2004 Jun. PMID 15174130

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 2-octaprenylphenol hydroxylase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 2-octaprenylphenol hydroxylase activity IEA
Inferred from Electronic Annotation
more info
  
enables 2-octaprenylphenol hydroxylase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables FAD binding IEA
Inferred from Electronic Annotation
more info
  
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in ubiquinone biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in ubiquinone biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within ubiquinone biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
part_of ubiquinone biosynthesis complex IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
2-octaprenylphenol 6-hydroxylase
NP_417382.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3051115..3052317 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417382.1 2-octaprenylphenol 6-hydroxylase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417382.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7EB43
    Conserved Domains (1) summary
    PRK08013
    Location:1 → 400
    PRK08013; oxidoreductase; Provisional
Nucleotide Protein
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