sad succinate semialdehyde dehydrogenase (NAD(P)(+)) Sad [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Gene symbol: sad
Gene description: succinate semialdehyde dehydrogenase (NAD(P)(+)) Sad
Primary source: ASAP:ABE-0005092
Locus tag: b1525
See related: ECOCYC:G6811
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK1518; yneI
Summary: Induced by exogenous succinate semialdehyde. [More information is available at EcoGene: EG13817]. Escherichia coli K-12 encodes two succinate semialdehyde dehydrogenases which differ in their ability to utilize NAD+ and NADP+. [More information is available at EcoCyc: G6811].
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NC_000913.3 Genomic Context describing neighboring genes

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Function	Evidence Code	Pubs
enables aldehyde dehydrogenase [NAD(P)+] activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEA Inferred from Electronic Annotation more info
enables protein homodimerization activity	IDA Inferred from Direct Assay more info	PubMed
enables succinate-semialdehyde dehydrogenase (NAD+) activity	IBA Inferred from Biological aspect of Ancestor more info
enables succinate-semialdehyde dehydrogenase (NAD+) activity	IDA Inferred from Direct Assay more info	PubMed
enables succinate-semialdehyde dehydrogenase (NAD+) activity	IEA Inferred from Electronic Annotation more info
enables succinate-semialdehyde dehydrogenase (NADP+) activity	IEA Inferred from Electronic Annotation more info
enables succinate-semialdehyde dehydrogenase [NAD(P)+] activity	IDA Inferred from Direct Assay more info	PubMed
enables succinate-semialdehyde dehydrogenase [NAD(P)+] activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within arginine catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in gamma-aminobutyric acid catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within gamma-aminobutyric acid catabolic process	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within gamma-aminobutyric acid catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nitrogen compound metabolic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within putrescine catabolic process	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within putrescine catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed

NP_416042.2

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The following sections contain reference sequences that belong to a specific genome build. Explain