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fepB ferric enterobactin ABC transporter periplasmic binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947538, updated on 23-Nov-2023

Summary

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Gene symbol
fepB
Gene description
ferric enterobactin ABC transporter periplasmic binding protein
Primary source
ASAP:ABE-0002038
Locus tag
b0592
See related
ECOCYC:EG10294
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0585
Summary
FepBCDG are components of a ferric enterobactin transport complex that is a member of the ATP-binding cassette (ABC) family of transporters. [More information is available at EcoCyc: EG10294].
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Genomic context

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Sequence:
NC_000913.3 (623554..624510, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ferric enterobactin ABC transporter membrane subunit FepG Neighboring gene ferric enterobactin ABC transporter membrane subunit FebD Neighboring gene enterobactin exporter EntS Neighboring gene isochorismate synthase EntC Neighboring gene 2,3-dihydroxybenzoate-AMP ligase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of an AU-rich translational enhancer within the Escherichia coli fepB leader RNA. Hook-Barnard IG, et al. J Bacteriol, 2007 Jun. PMID 17400738, Free PMC Article
  2. Nucleotide sequence and regulation of the Escherichia coli gene for ferrienterobactin transport protein FepB. Elkins MF, et al. J Bacteriol, 1989 Oct. PMID 2529253, Free PMC Article
  3. Two fep genes are required for ferrienterochelin uptake in Escherichia coli K-12. Pierce JR, et al. J Bacteriol, 1983 Jul. PMID 6223021, Free PMC Article
  4. Escherichia coli K-12 envelope proteins specifically required for ferrienterobactin uptake. Pierce JR, et al. J Bacteriol, 1986 Jun. PMID 3011753, Free PMC Article
  5. Structure, expression, and protein engineering of the pyruvate dehydrogenase complex of Escherichia coli. Guest JR, et al. Ann N Y Acad Sci, 1989. PMID 2699406

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: Binding of ferric enterobactin by the Escherichia coli periplasmic protein FepB.
  2. Data show that the translational enhancer-GUG organization in fepB results in an intermediate level of expression compared to the level with AUG.
    Title: Identification of an AU-rich translational enhancer within the Escherichia coli fepB leader RNA.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within ferric-enterobactin import into cell IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in iron import into cell NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in iron ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in outer membrane-bounded periplasmic space IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
 PubMed 
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ferric enterobactin ABC transporter periplasmic binding protein
NP_415124.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    623554..624510 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415124.1 ferric enterobactin ABC transporter periplasmic binding protein [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415124.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A827BGR7, A0A8T5YK89
    Conserved Domains (1) summary
    COG4592
    Location:1 → 318
    FepB; ABC-type Fe2+-enterobactin transport system, periplasmic component [Inorganic ion transport and metabolism]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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