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bacA undecaprenyl pyrophosphate phosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947551, updated on 4-Feb-2024

Summary

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Gene symbol
bacA
Gene description
undecaprenyl pyrophosphate phosphatase
Primary source
ASAP:ABE-0010034
Locus tag
b3057
See related
ECOCYC:EG11665
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3047; uppP
Summary
BacA(UppP) encodes 75% of the cell's UppP activity. [More information is available at EcoGene: EG11665]. The purified BacA protein exhibits undecaprenyl pyrophosphate phosphatase activity, but not undecaprenol phosphokinase activity . [More information is available at EcoCyc: EG11665].
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Genomic context

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Sequence:
NC_000913.3 (3203310..3204131, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative signal transduction protein (SH3 domain) Neighboring gene fused CCA tRNA nucleotidyltransferase/phosphohydrolase Neighboring gene dihydroneopterin aldolase Neighboring gene putative glycerol-3-phosphate acyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Membrane Topology and Biochemical Characterization of the Escherichia coli BacA Undecaprenyl-Pyrophosphate Phosphatase. Manat G, et al. PLoS One, 2015. PMID 26560897, Free PMC Article
  2. Periplasmic phosphorylation of lipid A is linked to the synthesis of undecaprenyl phosphate. Touzé T, et al. Mol Microbiol, 2008 Jan. PMID 18047581, Free PMC Article
  3. An Escherichia coli undecaprenyl-pyrophosphate phosphatase implicated in undecaprenyl phosphate recycling. Tatar LD, et al. Microbiology (Reading), 2007 Aug. PMID 17660416
  4. New members of the Escherichia coli sigmaE regulon identified by a two-plasmid system. Rezuchova B, et al. FEMS Microbiol Lett, 2003 Aug 8. PMID 12900013
  5. Identification of multiple genes encoding membrane proteins with undecaprenyl pyrophosphate phosphatase (UppP) activity in Escherichia coli. El Ghachi M, et al. J Biol Chem, 2005 May 13. PMID 15778224

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. all the different E. coli C55-PP phosphatases identified to date (BacA and PAP2, including PgpB, YbjG and LpxT) catalyze the dephosphorylation of C55-PP molecules on the same (outer) side of the plasma membrane
    Title: Membrane Topology and Biochemical Characterization of the Escherichia coli BacA Undecaprenyl-Pyrophosphate Phosphatase.
  2. there are multiple genes encoding membrane proteins with undecaprenyl pyrophosphate phosphatase (UppP) activity in Escherichia coli
    Title: Identification of multiple genes encoding membrane proteins with undecaprenyl pyrophosphate phosphatase (UppP) activity in Escherichia coli.
Submit: New GeneRIF Correction

Pathways from PubChem

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General protein information

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Preferred Names
undecaprenyl pyrophosphate phosphatase
NP_417529.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3203310..3204131 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417529.1 undecaprenyl pyrophosphate phosphatase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417529.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A827QUW5
    Conserved Domains (1) summary
    PRK00281
    Location:3 → 273
    PRK00281; undecaprenyl-diphosphate phosphatase
Nucleotide Protein
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