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srlA sorbitol-specific PTS enzyme IIC2 component [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947575, updated on 2-May-2024

Summary

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Gene symbol
srlA
Gene description
sorbitol-specific PTS enzyme IIC2 component
Primary source
ASAP:ABE-0008890
Locus tag
b2702
See related
ECOCYC:G8210
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2697; gutA; sbl; srlA-1
Summary
Membrane topology predictions using experimentally determined C terminus locations indicate that SrlA has 3 transmembrane helices and the C-terminus is located in the cytoplasm . [More information is available at EcoCyc: G8210].
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Genomic context

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Sequence:
NC_000913.3 (2825832..2826395)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene NMN aminohydrolase Neighboring gene membrane-bound lytic murein transglycosylase B Neighboring gene sorbitol-specific PTS enzyme IIBC1 component Neighboring gene sorbitol-specific PTS enzyme IIA component Neighboring gene sorbitol-6-phosphate 2-dehydrogenase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A specialized transducing phage, lambda psrlA, for the sorbitol phosphotransferase of Escherichia coli K12. Boronat A, et al. J Gen Microbiol, 1982 Mar. PMID 6281366
  2. Xylitol and D-arabitol toxicities due to derepressed fructose, galactitol, and sorbitol phosphotransferases of Escherichia coli. Reiner AM. J Bacteriol, 1977 Oct. PMID 334721, Free PMC Article
  3. Physical mapping of the srl recA region of Escherichia coli: analysis of Tn10 generated insertions and deletions. Willis DK, et al. Mol Gen Genet, 1981. PMID 6278241
  4. Proposed topology of the glucitol permeases of Escherichia coli and Clostridium acetobutylicum. Reizer J, et al. Curr Microbiol, 1996 Nov. PMID 8875915
  5. Genetic analysis of the Escherichia coli K-12 srl region. McEntee K. J Bacteriol, 1977 Dec. PMID 336611, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Process Evidence Code Pubs
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphoenolpyruvate-dependent sugar phosphotransferase system IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in phosphoenolpyruvate-dependent sugar phosphotransferase system NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in sorbitol transmembrane transport NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
part_of transmembrane transporter complex NAS
Non-traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
sorbitol-specific PTS enzyme IIC2 component
YP_026180.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2825832..2826395
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_026180.1 sorbitol-specific PTS enzyme IIC2 component [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for YP_026180.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A447X2C8
    Conserved Domains (1) summary
    TIGR00821
    Location:1 → 181
    EII-GUT; PTS system, glucitol/sorbitol-specific, IIC component
Nucleotide Protein
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