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ttdT L-tartrate:succinate antiporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947576, updated on 4-Apr-2024

Summary

Gene symbol
ttdT
Gene description
L-tartrate:succinate antiporter
Primary source
ASAP:ABE-0010056
Locus tag
b3063
See related
ECOCYC:EG12393
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3053; ygjC; ygjE
Summary
TtdT does not transport D-tartrate and can uptake succinate, although excretion of succinate is favored. [More information is available at EcoGene: EG12393]. TtdT is a putative tartrate/succinate antiporter belonging to the DASS family of di- and tri-carboxylic acid transporters. [More information is available at EcoCyc: EG12393].
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Genomic context

Sequence:
NC_000913.3 (3208024..3209487)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional activator Dan Neighboring gene L(+)-tartrate dehydratase subunit alpha Neighboring gene L(+)-tartrate dehydratase subunit beta Neighboring gene N(6)-L-threonylcarbamoyladenine synthase, TsaD subunit Neighboring gene 30S ribosomal subunit protein S21

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables antiporter activity IEA
Inferred from Electronic Annotation
more info
 
enables antiporter activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
L-tartrate:succinate antiporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3208024..3209487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417535.1 L-tartrate:succinate antiporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417535.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7E8R2
    Conserved Domains (1) summary
    pfam00939
    Location:4487
    Na_sulph_symp; Sodium:sulfate symporter transmembrane region