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argG argininosuccinate synthetase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947590, updated on 2-May-2024

Summary

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Gene symbol
argG
Gene description
argininosuccinate synthetase
Primary source
ASAP:ABE-0010428
Locus tag
b3172
See related
ECOCYC:EG10068
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3161
Summary
The subunit structure is not known. [More information is available at EcoCyc: EG10068].
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Genomic context

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Sequence:
NC_000913.3 (3318637..3319980)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ribosome maturation factor RimP Neighboring gene tRNA-Met Neighboring gene putative hydrolase YhbX Neighboring gene tRNA-Leu

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Substrate induced conformational changes in argininosuccinate synthetase. Lemke CT, et al. J Biol Chem, 2002 Apr 12. PMID 11809762
  2. Transcription regulation coupling of the divergent argG and metY promoters in Escherichia coli K-12. Krin E, et al. J Bacteriol, 2003 May. PMID 12730174, Free PMC Article
  3. Recognition of overlapping nucleotides by AraC and the sigma subunit of RNA polymerase. Dhiman A, et al. J Bacteriol, 2000 Sep. PMID 10960090, Free PMC Article
  4. Complementation of argG and hisA mutations of Escherichia coli by DNA cloned from the archaebacterium Methanococcus voltae. Wood AG, et al. J Bacteriol, 1983 Oct. PMID 6352676, Free PMC Article
  5. Sequences of the genes encoding argininosuccinate synthetase in Escherichia coli and Saccharomyces cerevisiae: comparison with methanogenic archaebacteria and mammals. Van Vliet F, et al. Gene, 1990 Oct 30. PMID 2123815

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. N-terminus verified by Edman degradation on mature peptide
    Title: Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables argininosuccinate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables argininosuccinate synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables argininosuccinate synthase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in arginine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in arginine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in argininosuccinate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in urea cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
argininosuccinate synthetase
NP_417640.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3318637..3319980
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417640.1 argininosuccinate synthetase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417640.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376CZC6, A0A376JTA2, A0A785EPM8
    Conserved Domains (1) summary
    PRK05370
    Location:1 → 446
    PRK05370; argininosuccinate synthase; Validated
Nucleotide Protein
Heading Accession and Version

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