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uxaA D-altronate dehydratase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947603, updated on 23-Nov-2023

Summary

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Gene symbol
uxaA
Gene description
D-altronate dehydratase
Primary source
ASAP:ABE-0010164
Locus tag
b3091
See related
ECOCYC:EG12734
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3082; ygjW
Summary
ExuR regulon. [More information is available at EcoGene: EG12734]. Altronate dehydratase catalyzes the final reaction of the galaturonate branch of the hexuronate degradation pathway . [More information is available at EcoCyc: EG12734].
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Genomic context

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Sequence:
NC_000913.3 (3241827..3243314, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene serine/threonine:Na(+) symporter Neighboring gene inner membrane protein Neighboring gene D-glucoronate/D-galacturonate isomerase Neighboring gene hexuronate transporter

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Uronic acid metabolism in bacteria. III. Purification and properties of D-altronic acid and D-mannonic acid dehydrases in Escherichia coli. SMILEY JD, et al. J Biol Chem, 1960 Jun. PMID 13831814
  2. D-Mannonate and D-altronate dehydratases of Escherichia coli K12. Robert-Baudouy J, et al. Methods Enzymol, 1982. PMID 6759855
  3. The gene for ribosomal protein S21, rpsU, maps close to dnaG at 66.5 min on the Escherichia coli chromosomal linkage map. Dabbs ER. J Bacteriol, 1980 Nov. PMID 7000750, Free PMC Article
  4. Overexpression of the LexA-regulated tisAB RNA in E. coli inhibits SOS functions; implications for regulation of the SOS response. Weel-Sneve R, et al. Nucleic Acids Res, 2008 Nov. PMID 18832374, Free PMC Article
  5. Physical mapping of the exuT and uxaC operators by use of exu plasmids and generation of deletion mutants in vitro. Mata-Gilsinger M, et al. J Bacteriol, 1983 Sep. PMID 6309752, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables altronate dehydratase activity IEA
Inferred from Electronic Annotation
more info
  
enables ferrous iron binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in D-galacturonate catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within D-galacturonate catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
D-altronate dehydratase
NP_417562.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3241827..3243314 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417562.1 D-altronate dehydratase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417562.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7XAA4
    Conserved Domains (2) summary
    cd11613
    Location:2 → 81
    SAF_AH_GD; Domains similar to fish antifreeze type III protein
    pfam04295
    Location:106 → 494
    GD_AH_C; D-galactarate dehydratase / Altronate hydrolase, C-terminus
Nucleotide Protein
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