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sstT serine/threonine:Na(+) symporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947605, updated on 2-May-2024

Summary

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Gene symbol
sstT
Gene description
serine/threonine:Na(+) symporter
Primary source
ASAP:ABE-0010159
Locus tag
b3089
See related
ECOCYC:EG12732
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3080; ygjU
Summary
The YgjU/SstT protein is a member of the DAACS family of sodium ion coupled serine/threonine symporters. [More information is available at EcoCyc: EG12732].
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Genomic context

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Sequence:
NC_000913.3 (3239944..3241188)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative oxidoreductase YgjR Neighboring gene putative membrane-bound redox modulator Alx Neighboring gene inner membrane protein Neighboring gene D-altronate dehydratase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Purification, reconstitution, and characterization of Na(+)/serine symporter, SstT, of Escherichia coli. Kim YM, et al. J Biochem, 2002 Jul. PMID 12097162
  2. Cloning and expression of the gene for the Na+-coupled serine transporter from Escherichia coli and characteristics of the transporter. Ogawa W, et al. J Bacteriol, 1998 Dec. PMID 9852024, Free PMC Article
  3. Properties of a Na+-coupled serine-threonine transport system in Escherichia coli. Hama H, et al. Biochim Biophys Acta, 1987 Dec 11. PMID 2825778
  4. The small RNA GcvB regulates sstT mRNA expression in Escherichia coli. Pulvermacher SC, et al. J Bacteriol, 2009 Jan. PMID 18952787, Free PMC Article
  5. Isolation and characterization of an Escherichia coli mutant lacking the major serine transporter, and cloning of a serine transporter gene. Ogawa W, et al. J Biochem, 1997 Dec. PMID 9498571

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables L-serine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables L-threonine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables amino acid transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables neutral L-amino acid transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables neutral L-amino acid:sodium symporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables neutral L-amino acid:sodium symporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables symporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-serine transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within amino acid transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in serine transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within serine transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in serine transport IEA
Inferred from Electronic Annotation
more info
  
involved_in threonine transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in threonine transport IEA
Inferred from Electronic Annotation
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
serine/threonine:Na(+) symporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3239944..3241188
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417560.1 serine/threonine:Na(+) symporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417560.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376TS49
    Conserved Domains (1) summary
    PRK13628
    Location:3 → 404
    PRK13628; serine/threonine transporter SstT; Provisional
Nucleotide Protein
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