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pabA aminodeoxychorismate synthase subunit 2 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947873, updated on 2-May-2024

Summary

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Gene symbol
pabA
Gene description
aminodeoxychorismate synthase subunit 2
Primary source
ASAP:ABE-0010983
Locus tag
b3360
See related
ECOCYC:EG10682
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3348
Summary
Component II provides the glutamine amidotransferase activity. [More information is available at EcoCyc: EG10682].
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Genomic context

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Sequence:
NC_000913.3 (3490266..3490829, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative transporter YhfK Neighboring gene N-acetylornithine aminotransferase/N-succinyldiaminopimelate aminotransferase Neighboring gene protein YrfJ Neighboring gene putative adenosine monophosphate--protein transferase Fic Neighboring gene DUF2559 domain-containing protein YhfG Neighboring gene peptidyl-prolyl cis-trans isomerase A

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Nucleotide sequence of Escherichia coli pabA and its evolutionary relationship to trp(G)D. Kaplan JB, et al. J Mol Biol, 1983 Aug 15. PMID 6350604
  2. Biosynthesis of 4-aminobenzoate in Escherichia coli. Huang M, et al. J Bacteriol, 1970 Jun. PMID 4914080, Free PMC Article
  3. Escherichia coli aminodeoxychorismate synthase: analysis of pabB mutations affecting catalysis and subunit association. Rayl EA, et al. Biochim Biophys Acta, 1996 Jun 7. PMID 8679677
  4. p-Aminobenzoate synthesis in Escherichia coli: mutational analysis of three conserved amino acid residues of the amidotransferase PabA. Roux B, et al. Biochemistry, 1993 Apr 13. PMID 8096767
  5. Genetic analysis of mutant strains of Escherichia coli requiring p-aminobenzoic acid for growth. Huang M, et al. J Bacteriol, 1967 Jun. PMID 5337773, Free PMC Article

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4-amino-4-deoxychorismate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables 4-amino-4-deoxychorismate synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables 4-amino-4-deoxychorismate synthase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
contributes_to anthranilate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in aromatic amino acid family biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in folic acid biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in folic acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in glutamine metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within para-aminobenzoic acid biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in tetrahydrofolate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tetrahydrofolate biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in tetrahydrofolate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in tetrahydrofolate biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in tryptophan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of aminodeoxychorismate synthase complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of aminodeoxychorismate synthase complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
aminodeoxychorismate synthase subunit 2
NP_417819.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3490266..3490829 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417819.1 aminodeoxychorismate synthase subunit 2 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417819.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A827XTY3, A0A8S7E8A6
    Conserved Domains (1) summary
    PRK08007
    Location:1 → 187
    PRK08007; aminodeoxychorismate synthase component 2
Nucleotide Protein
Heading Accession and Version

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