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frlA fructoselysine/psicoselysine transporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947878, updated on 4-Feb-2024

Summary

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Gene symbol
frlA
Gene description
fructoselysine/psicoselysine transporter
Primary source
ASAP:ABE-0011019
Locus tag
b3370
See related
ECOCYC:EG12908
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3358; yhfM
Summary
FrlA is an uncharacterized member of the APC superfamily of amino acid transporters . [More information is available at EcoCyc: EG12908].
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Genomic context

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Sequence:
NC_000913.3 (3499910..3501247)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene siroheme synthase Neighboring gene DUF4223 domain-containing lipoprotein YhfL Neighboring gene fructoselysine 6-phosphate deglycase Neighboring gene fructoselysine 3-epimerase Neighboring gene fructoselysine 6-kinase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of glucoselysine-6-phosphate deglycase, an enzyme involved in the metabolism of the fructation product glucoselysine. Wiame E, et al. Biochem J, 2005 Dec 1. PMID 16153181, Free PMC Article
  2. Identification of a pathway for the utilization of the Amadori product fructoselysine in Escherichia coli. Wiame E, et al. J Biol Chem, 2002 Nov 8. PMID 12147680
  3. Fructoselysine 3-epimerase, an enzyme involved in the metabolism of the unusual Amadori compound psicoselysine in Escherichia coli. Wiame E, et al. Biochem J, 2004 Mar 15. PMID 14641112, Free PMC Article
  4. The amino acid/polyamine/organocation (APC) superfamily of transporters specific for amino acids, polyamines and organocations. Jack DL, et al. Microbiology (Reading), 2000 Aug. PMID 10931886
  5. Global topology analysis of the Escherichia coli inner membrane proteome. Daley DO, et al. Science, 2005 May 27. PMID 15919996

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables L-amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in L-alpha-amino acid transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within fructoselysine catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
fructoselysine/psicoselysine transporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3499910..3501247
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417829.2 fructoselysine/psicoselysine transporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417829.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A0E1SWF7, A0A1U9SVX0, A0A1X3JC60, A0A236GUN3, A0A2A2XEX8, A0A7I6H3I0, A0A9P2I7C3, A0AA35AM85, A7ZSP6, E1INV6, J7QWL9
    Conserved Domains (1) summary
    PRK11357
    Location:1 → 445
    frlA; amino acid permease
Nucleotide Protein
Heading Accession and Version

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