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gph phosphoglycolate phosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947895, updated on 2-May-2024

Summary

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Gene symbol
gph
Gene description
phosphoglycolate phosphatase
Primary source
ASAP:ABE-0011058
Locus tag
b3385
See related
ECOCYC:EG11871
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3372; yhfE
Summary
HAD superfamily. gph is a non-essential gene. [More information is available at EcoGene: EG11871]. The gph gene encodes a haloacid dehalogenase (HAD)-like phosphatase family enzyme with 2-phosphoglycolate phosphatase activity . [More information is available at EcoCyc: EG11871].
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Genomic context

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Sequence:
NC_000913.3 (3513631..3514389, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene PRD domain-containing protein YhfY Neighboring gene putative DNA-binding transcriptional regulator YhfZ Neighboring gene tryptophan--tRNA ligase Neighboring gene ribulose-phosphate 3-epimerase Neighboring gene DNA adenine methyltransferase Neighboring gene cell division protein DamX

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Role of 2-phosphoglycolate phosphatase of Escherichia coli in metabolism of the 2-phosphoglycolate formed in DNA repair. Teresa Pellicer M, et al. J Bacteriol, 2003 Oct. PMID 13129953, Free PMC Article
  2. Fluorescence two-dimensional difference gel electrophoresis and mass spectrometry based proteomic analysis of Escherichia coli. Yan JX, et al. Proteomics, 2002 Dec. PMID 12469338
  3. The Escherichia coli proteome: past, present, and future prospects. Han MJ, et al. Microbiol Mol Biol Rev, 2006 Jun. PMID 16760308, Free PMC Article
  4. Characterization of three genes in the dam-containing operon of Escherichia coli. Lyngstadaas A, et al. Mol Gen Genet, 1995 Jun 10. PMID 7603433
  5. Multicopy suppression underpins metabolic evolvability. Patrick WM, et al. Mol Biol Evol, 2007 Dec. PMID 17884825, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables chloride ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphoglycolate phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables phosphoglycolate phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphoglycolate phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in DNA repair IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within DNA repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glycolate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
phosphoglycolate phosphatase
NP_417844.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3513631..3514389 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417844.1 phosphoglycolate phosphatase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417844.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A6C9Q9N9, A0A8S7EAW7
    Conserved Domains (1) summary
    PRK13222
    Location:2 → 244
    PRK13222; N-acetylmuramic acid 6-phosphate phosphatase MupP
Nucleotide Protein
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