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gntT high-affinity gluconate transporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947924, updated on 11-Apr-2024

Summary

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Gene symbol
gntT
Gene description
high-affinity gluconate transporter
Primary source
ASAP:ABE-0011148
Locus tag
b3415
See related
ECOCYC:EG12380
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3402; gntM; gntTalpha; usgA; yhgC
Summary
IT (Ion Transporter) superfamily (Prakash, 2003). [More information is available at EcoGene: EG12380]. GntT is one of four known transporters for gluconate in Escherichia coli, the others being the homologous GntU, GntP and IdnT transporters. [More information is available at EcoCyc: EG12380].
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Genomic context

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Sequence:
NC_000913.3 (3546559..3547875)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA utilization protein YhgH Neighboring gene iron-sulfur cluster carrier protein NfuA Neighboring gene 4-alpha-glucanotransferase Neighboring gene maltodextrin phosphorylase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A mutation affecting gluconate catabolism in Escherichia coli: the locus for the main high affinity transport. De Rekarte UD, et al. Acta Cient Venez, 1994. PMID 8731292
  2. Selection of lacZ operon fusions in genes of gluconate metabolism in E. coli. characterization of a gntT::lacZ fusion. Porco A, et al. Acta Cient Venez, 1991. PMID 1843569
  3. Positive and negative transcriptional regulation of the Escherichia coli gluconate regulon gene gntT by GntR and the cyclic AMP (cAMP)-cAMP receptor protein complex. Peekhaus N, et al. J Bacteriol, 1998 Apr. PMID 9537375, Free PMC Article
  4. Characterization of the gntT gene encoding a high-affinity gluconate permease in Escherichia coli. Izu H, et al. Gene, 1997 Oct 15. PMID 9358057
  5. Molecular genetic characterization of the Escherichia coli gntT gene of GntI, the main system for gluconate metabolism. Porco A, et al. J Bacteriol, 1997 Mar. PMID 9045817, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables gluconate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables gluconate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables gluconate transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in D-gluconate catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in D-gluconate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in gluconate transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in gluconate transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within gluconate transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in organic substance transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
high-affinity gluconate transporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3546559..3547875
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_026217.1 high-affinity gluconate transporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for YP_026217.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7D7DXK8, F4V7B2
    Conserved Domains (1) summary
    PRK14984
    Location:1 → 438
    PRK14984; gluconate transporter
Nucleotide Protein
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