livH branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

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Gene symbol: livH
Gene description: branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH
Primary source: ASAP:ABE-0011290
Locus tag: b3457
See related: ECOCYC:EG10538
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK3441; hrbB; hrbC; hrbD
Summary: LivFGHMJ and LivFGHMK are two ATP-dependent high-affinity branched-chain amino acid transport system and are members of the ATP Binding Cassette (ABC) Superfamily of transporters . [More information is available at EcoCyc: EG10538].
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Genomic context

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Sequence:: NC_000913.3 (3595477..3596403, complement)

NC_000913.3 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by EcoCyc

Function	Evidence Code	Pubs
enables L-isoleucine transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables L-isoleucine transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables L-leucine transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables L-leucine transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables L-phenylalanine transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables L-phenylalanine transmembrane transporter activity	IDA Inferred from Direct Assay more info	PubMed
enables L-valine transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables L-valine transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables branched-chain amino acid transmembrane transporter activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in D-alanine transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in L-alanine transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in L-isoleucine import across plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in L-leucine import across plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within L-leucine import across plasma membrane	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in L-valine transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within L-valine transmembrane transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in amino acid transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within branched-chain amino acid transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in branched-chain amino acid transport	NAS Non-traceable Author Statement more info	PubMed
acts_upstream_of_or_within isoleucine transmembrane transport	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in phenylalanine transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within phenylalanine transport	IDA Inferred from Direct Assay more info	PubMed
involved_in phenylalanine transport	NAS Non-traceable Author Statement more info	PubMed
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing	NAS Non-traceable Author Statement more info	PubMed
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing	RCA inferred from Reviewed Computational Analysis more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	NAS Non-traceable Author Statement more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	ISM Inferred from Sequence Model more info	PubMed

General protein information

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Preferred Names: branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH

NP_417914.1

EC 7.4.2.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_000913.3 Reference assembly

Range

3595477..3596403 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NP_417914.1 branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH [Escherichia coli str. K-12 substr. MG1655]

See identical proteins and their annotated locations for NP_417914.1

Status: PROVISIONAL

UniProtKB/TrEMBL

A0A5B9ARQ6

Conserved Domains (1) summary

PRK10740
Location:1 → 308

PRK10740; high-affinity branched-chain amino acid ABC transporter permease LivH