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livG branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947967, updated on 11-Apr-2024

Summary

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Gene symbol
livG
Gene description
branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG
Primary source
ASAP:ABE-0011284
Locus tag
b3455
See related
ECOCYC:EG10537
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3439; hrbB; hrbC; hrbD
Summary
LivFGHMJ and LivFGHMK are two ATP-dependent high-affinity branched-chain amino acid transport system and are members of the ATP Binding Cassette (ABC) Superfamily of transporters . [More information is available at EcoCyc: EG10537].
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Genomic context

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Sequence:
NC_000913.3 (3593439..3594206, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene sn-glycerol 3-phosphate ABC transporter periplasmic binding protein Neighboring gene branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivF Neighboring gene branched chain amino acid/phenylalanine ABC transporter membrane subunit LivM Neighboring gene branched chain amino acid/phenylalanine ABC transporter membrane subunit LivH Neighboring gene L-leucine/L-phenylalanine ABC transporter periplasmic binding protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transport of L-4-azaleucine in Escherichia coli. Harrison LI, et al. J Bacteriol, 1975 Jun. PMID 238951, Free PMC Article
  2. Genetic and biochemical studies of transport systems for branched-chain amino acids in Escherichia coli K-12: isolation and properties of mutants defective in leucine-repressible transport activities. Yamato I, et al. J Bacteriol, 1980 Oct. PMID 6998958, Free PMC Article
  3. Structural and functional analysis of cloned DNA containing genes responsible for branched-chain amino acid transport in Escherichia coli. Oxender DL, et al. Proc Natl Acad Sci U S A, 1980 Mar. PMID 6445555, Free PMC Article
  4. The complete nucleotide sequences of the Escherichia coli LIV-BP and LS-BP genes. Implications for the mechanism of high-affinity branched-chain amino acid transport. Landick R, et al. J Biol Chem, 1985 Jul 15. PMID 3891753
  5. Identification of livG, a membrane-associated component of the branched-chain amino acid transport in Escherichia coli. Nazos PM, et al. J Bacteriol, 1985 Sep. PMID 2993238, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding ISM
Inferred from Sequence Model
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
  
enables L-isoleucine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables L-isoleucine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables L-phenylalanine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables L-phenylalanine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables L-valine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables L-valine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables branched-chain amino acid transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in D-alanine transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in L-alanine transport IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in L-isoleucine import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in L-valine import across plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within L-valine transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within branched-chain amino acid transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in branched-chain amino acid transport NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within isoleucine transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within phenylalanine transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phenylalanine transport NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing NAS
Non-traceable Author Statement
more info
 PubMed 
part_of ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane NAS
Non-traceable Author Statement
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG
NP_417912.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3593439..3594206 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417912.1 branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417912.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7D7F9S9, A0A827XTT9
    Conserved Domains (1) summary
    PRK11300
    Location:1 → 255
    livG; leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Nucleotide Protein
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