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hycB formate hydrogenlyase subunit HycB [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948002, updated on 6-Oct-2023

Summary

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Gene symbol
hycB
Gene description
formate hydrogenlyase subunit HycB
Primary source
ASAP:ABE-0008950
Locus tag
b2724
See related
ECOCYC:EG10475
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2719; hevB
Summary
FhlA regulon. [More information is available at EcoGene: EG10475]. HycB is thought to code for a subunit of hydrogenase 3, a peptide of the [4Fe-4S] ferredoxin type, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase . [More information is available at EcoCyc: EG10475].
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Genomic context

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Sequence:
NC_000913.3 (2849238..2849849, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene formate hydrogenlyase subunit HycE Neighboring gene formate hydrogenlyase subunit HycD Neighboring gene formate hydrogenlyase subunit HycC Neighboring gene regulator of the transcriptional regulator FhlA Neighboring gene hydrogenase 3 nickel incorporation protein HypA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Microbial reduction of technetium by Escherichia coli and Desulfovibrio desulfuricans: enhancement via the use of high-activity strains and effect of process parameters. Lloyd JR, et al. Biotechnol Bioeng, 1999. PMID 10567070
  2. Reduction and removal of heptavalent technetium from solution by Escherichia coli. Lloyd JR, et al. J Bacteriol, 1997 Mar. PMID 9068649, Free PMC Article
  3. Mechanism of regulation of the formate-hydrogenlyase pathway by oxygen, nitrate, and pH: definition of the formate regulon. Rossmann R, et al. Mol Microbiol, 1991 Nov. PMID 1779767
  4. Relationship between formate hydrogen lyase and proton-potassium pump under heterolactic fermentation in Escherichia coli: functional multienzyme associations in the cell membrane. Trchounian AA, et al. Membr Cell Biol, 2000. PMID 10926369
  5. Relationship between the F0F1-ATPase and the K(+)-transport system within the membrane of anaerobically grown Escherichia coli. N,N'-dicyclohexylcarbodiimide-sensitive ATPase activity in mutants with defects in K(+)-transport. Trchounian AA, et al. J Bioenerg Biomembr, 1994 Oct. PMID 7896771

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 4 iron, 4 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables 4 iron, 4 sulfur cluster binding RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in anaerobic electron transport chain IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in anaerobic respiration IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in formate oxidation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in glucose catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of formate dehydrogenase complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
formate hydrogenlyase subunit HycB
NP_417204.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2849238..2849849 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417204.1 formate hydrogenlyase subunit HycB [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417204.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A376D3R9, A0A376MGR1
    Conserved Domains (1) summary
    cd10554
    Location:4 → 167
    HycB_like; HycB, HydN and similar proteins
Nucleotide Protein
Heading Accession and Version

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