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arsB arsenite/antimonite:H(+) antiporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948011, updated on 11-Apr-2024

Summary

Gene symbol
arsB
Gene description
arsenite/antimonite:H(+) antiporter
Primary source
ASAP:ABE-0011437
Locus tag
b3502
See related
ECOCYC:EG12236
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
arsF; ECK3487
Summary
ArsB can function alone using PMF to drive transport, as is the case with the chromosomal ArsB, which lacks the ArsA ATPase; ArsB proteins can use ATP to drive efflux if ArsA is present. [More information is available at EcoGene: EG12236]. Based on sequence similarity with the R773-plasmid encoded arsenite resistance operon, ArsB is a transporter and ArsC is an arsenate reductase . [More information is available at EcoCyc: EG12236].
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Genomic context

Sequence:
NC_000913.3 (3648935..3650224)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DNA-binding transcriptional repressor ArsR Neighboring gene arsenate reductase Neighboring gene pseudo Neighboring gene IS5 family transposase and trans-activator

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Process Evidence Code Pubs
acts_upstream_of_or_within antimonite transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in arsenite transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within arsenite transport IDA
Inferred from Direct Assay
more info
PubMed 
involved_in arsenite transport IEA
Inferred from Electronic Annotation
more info
 
involved_in response to arsenic-containing substance IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
arsenite/antimonite:H(+) antiporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3648935..3650224
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417959.4 arsenite/antimonite:H(+) antiporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417959.4

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A827Y137, A0AA87GP70
    Conserved Domains (1) summary
    PRK15445
    Location:2428
    PRK15445; arsenical efflux pump membrane protein ArsB