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yiaK 2,3-diketo-L-gulonate reductase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948096, updated on 4-Apr-2024

Summary

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Gene symbol
yiaK
Gene description
2,3-diketo-L-gulonate reductase
Primary source
ASAP:ABE-0011682
Locus tag
b3575
See related
ECOCYC:EG12279
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3564
Summary
The yiaK gene encodes a 2,3-diketo-L-gulonate reductase . [More information is available at EcoCyc: EG12279].
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Genomic context

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Sequence:
NC_000913.3 (3742733..3743731)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative electron transport protein YsaA Neighboring gene DNA-binding transcriptional repressor PlaR Neighboring gene DUF386 domain-containing protein YiaL Neighboring gene 2,3-diketo-L-gulonate:Na(+) symporter - membrane subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A novel NAD-binding protein revealed by the crystal structure of 2,3-diketo-L-gulonate reductase (YiaK). Forouhar F, et al. J Biol Chem, 2004 Mar 26. PMID 14718529
  2. A rare 920-kilobase chromosomal inversion mediated by IS1 transposition causes constitutive expression of the yiaK-S operon for carbohydrate utilization in Escherichia coli. Badía J, et al. J Biol Chem, 1998 Apr 3. PMID 9525947
  3. Quantitative whole-genome analysis of DNA-protein interactions by in vivo methylase protection in E. coli. Tavazoie S, et al. Nat Biotechnol, 1998 Jun. PMID 9624689
  4. Regulation of expression of the yiaKLMNOPQRS operon for carbohydrate utilization in Escherichia coli: involvement of the main transcriptional factors. Ibañez E, et al. J Bacteriol, 2000 Aug. PMID 10913096, Free PMC Article
  5. Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes. Sofia HJ, et al. Nucleic Acids Res, 1994 Jul 11. PMID 8041620, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General protein information

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Preferred Names
2,3-diketo-L-gulonate reductase
NP_418032.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3742733..3743731
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418032.1 2,3-diketo-L-gulonate reductase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418032.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AA87EC66, A0AA87JST2
    Conserved Domains (1) summary
    PRK13260
    Location:1 → 332
    PRK13260; 2,3-diketo-L-gulonate reductase; Provisional
Nucleotide Protein
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