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xylA xylose isomerase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948141, updated on 4-Feb-2024

Summary

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Gene symbol
xylA
Gene description
xylose isomerase
Primary source
ASAP:ABE-0011639
Locus tag
b3565
See related
ECOCYC:EG11074
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3554
Summary
Xylose isomerase catalyzes the first reaction in the catabolism of D-xylose . [More information is available at EcoCyc: EG11074].
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Genomic context

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Sequence:
NC_000913.3 (3729443..3730765, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene PF05360 family inner membrane protein YiaB Neighboring gene xylulokinase Neighboring gene ncRNA Neighboring gene xylose ABC transporter periplasmic binding protein Neighboring gene xylose ABC transporter ATP binding subunit Neighboring gene xylose ABC transporter membrane subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. [Cloning of Escherichia coli K12 xylose isomerase (glucose isomerase) and studying the enzymatic properties of its expression product]. Rozanov AS, et al. Prikl Biokhim Mikrobiol, 2009 Jan-Feb. PMID 19235507
  2. Influence of divalent cations on the structural thermostability and thermal inactivation kinetics of class II xylose isomerases. Epting KL, et al. FEBS J, 2005 Mar. PMID 15752361
  3. Amplification of D-xylose and D-glucose isomerase activities in Escherichia coli by gene cloning. Wovcha MG, et al. Appl Environ Microbiol, 1983 Apr. PMID 6344793, Free PMC Article
  4. Xylose isomerase from Escherichia coli. Characterization of the protein and the structural gene. Schellenberg GD, et al. J Biol Chem, 1984 Jun 10. PMID 6327696
  5. Identification of essential histidine residues in the active site of Escherichia coli xylose (glucose) isomerase. Batt CA, et al. Proc Natl Acad Sci U S A, 1990 Jan. PMID 2405386, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein homodimerization activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables xylose isomerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables xylose isomerase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables xylose isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables xylose isomerase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in D-xylose catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within D-xylose catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in D-xylose metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
xylose isomerase
NP_418022.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3729443..3730765 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418022.1 xylose isomerase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418022.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9ADI8, A0A826IYQ1, A0A827QMD9
    Conserved Domains (1) summary
    PRK05474
    Location:3 → 439
    PRK05474; xylose isomerase; Provisional
Nucleotide Protein
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