U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

waaQ lipopolysaccharide core heptosyltransferase 3 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948155, updated on 4-Apr-2024

Summary

Go to the top of the page Help
Gene symbol
waaQ
Gene description
lipopolysaccharide core heptosyltransferase 3
Primary source
ASAP:ABE-0011870
Locus tag
b3632
See related
ECOCYC:EG11341
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3622; rfaQ
Summary
The lipopolysaccharide of Escherichia coli K-12 consists of two major components: the hydrophobic lipid A moiety inserted into the outer membrane and the phosphorylated core oligosaccharide . [More information is available at EcoCyc: EG11341].
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Sequence:
NC_000913.3 (3807064..3808098, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene lipopolysaccharide core biosynthesis protein WaaS Neighboring gene lipopolysaccharide core heptose (I) kinase Neighboring gene lipopolysaccharide glucosyltransferase I Neighboring gene ncRNA Neighboring gene KDO transferase

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Cloning and characterization of the Escherichia coli Heptosyltransferase III: Exploring substrate specificity in lipopolysaccharide core biosynthesis. Mudapaka J, et al. FEBS Lett, 2015 Jun 4. PMID 25957775
  2. Glycosyltransferase functions of E. coli O-antigens. Lundborg M, et al. Glycobiology, 2010 Mar. PMID 19926726
  3. The presence of OMP inclusion bodies in a Escherichia coli K-12 mutated strain is not related to lipopolysaccharide structure. Corsaro MM, et al. J Biochem, 2009 Aug. PMID 19364804
  4. An Escherichia coli MG1655 lipopolysaccharide deep-rough core mutant grows and survives in mouse cecal mucus but fails to colonize the mouse large intestine. Møller AK, et al. Infect Immun, 2003 Apr. PMID 12654836, Free PMC Article
  5. Identification by Tn10 transposon mutagenesis of host factors involved in the biosynthesis of K99 fimbriae of Escherichia coli: effect of LPS core mutations. Pilipcinec E, et al. FEMS Microbiol Lett, 1994 Oct 15. PMID 7988890

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data indicate that Heptosyltransferase III (HepIII; WaaQ protein) catalyzes the addition of an L-glycero-D-manno-heptose (Hep) residue to the growing lipopolysaccharide (LPS) core via an alpha(1-->7) bond.
    Title: Cloning and characterization of the Escherichia coli Heptosyltransferase III: Exploring substrate specificity in lipopolysaccharide core biosynthesis.
Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

General gene information

Go to the top of the page Help

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ADP-heptose-lipopolysaccharide heptosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables lipopolysaccharide core heptosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in lipopolysaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in lipopolysaccharide core region biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in lipopolysaccharide core region biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within lipopolysaccharide core region biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
lipopolysaccharide core heptosyltransferase 3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3807064..3808098 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418089.1 lipopolysaccharide core heptosyltransferase 3 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418089.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    O68210
    Conserved Domains (1) summary
    PRK10422
    Location:1 → 340
    PRK10422; lipopolysaccharide core biosynthesis protein; Provisional
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.