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dgoK 2-dehydro-3-deoxygalactonokinase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948207, updated on 4-Apr-2024

Summary

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Gene symbol
dgoK
Gene description
2-dehydro-3-deoxygalactonokinase
Primary source
ASAP:ABE-0012076
Locus tag
b3693
See related
ECOCYC:EG20051
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3686; yidV
Summary
2-dehydro-3-deoxygalactonate kinase catalyzes the second reaction in the degradation of D-galactonate, the ATP-dependent phosphorylation of 2-dehydro-3-deoxygalactonate . [More information is available at EcoCyc: EG20051].
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Genomic context

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Sequence:
NC_000913.3 (3873596..3874474, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene colicin M resistance protein Neighboring gene D-galactonate:H(+) symporter Neighboring gene D-galactonate dehydratase Neighboring gene 2-dehydro-3-deoxy-6-phosphogalactonate aldolase Neighboring gene DNA-binding transcriptional regulator DgoR Neighboring gene putative lipoprotein YidX Neighboring gene sugar phosphatase YidA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A functionally diverse enzyme superfamily that abstracts the alpha protons of carboxylic acids. Babbitt PC, et al. Science, 1995 Feb 24. PMID 7855594
  2. Identification of genes affecting lycopene accumulation in Escherichia coli using a shot-gun method. Kang MJ, et al. Biotechnol Bioeng, 2005 Sep 5. PMID 15898075
  3. The utilisation of D-galactonate and D-2-oxo-3-deoxygalactonate by Escherichia coli K-12. Biochemical and genetical studies. Cooper RA. Arch Microbiol, 1978 Aug 1. PMID 211976
  4. D-Galactonate utilisation by enteric bacteria. The catabolic pathway in Escherichia coli. Deacon J, et al. FEBS Lett, 1977 May 15. PMID 324806
  5. Molecular and Functional Insights into the Regulation of d-Galactonate Metabolism by the Transcriptional Regulator DgoR in Escherichia coli. Singh B, et al. J Bacteriol, 2019 Feb 15. PMID 30455279, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 2-dehydro-3-deoxygalactonokinase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables 2-dehydro-3-deoxygalactonokinase activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in D-galactonate catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within D-galactonate catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in carbohydrate phosphorylation IEA
Inferred from Electronic Annotation
more info
  
involved_in phosphorylation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
2-dehydro-3-deoxygalactonokinase
NP_418148.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3873596..3874474 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418148.1 2-dehydro-3-deoxygalactonokinase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418148.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A641IYM0, A0A6N8R9F2
    Conserved Domains (1) summary
    COG3734
    Location:3 → 292
    DgoK; 2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]
Nucleotide Protein
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