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rffH glucose-1-phosphate thymidylyltransferase 2 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948299, updated on 2-May-2024

Summary

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Gene symbol
rffH
Gene description
glucose-1-phosphate thymidylyltransferase 2
Primary source
ASAP:ABE-0012379
Locus tag
b3789
See related
ECOCYC:EG11454
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3781; yifG
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Genomic context

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Sequence:
NC_000913.3 (3973608..3974489)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene UDP-N-acetylglucosamine 2-epimerase Neighboring gene UDP-N-acetyl-D-mannosamine dehydrogenase Neighboring gene dTDP-glucose 4,6-dehydratase 2 Neighboring gene RffC Neighboring gene dTDP-4-dehydro-6-deoxy-D-glucose transaminase Neighboring gene lipid IIIECA flippase Neighboring gene TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure of Escherichia coli glucose-1-phosphate thymidylyltransferase (RffH) complexed with dTTP and Mg2+. Sivaraman J, et al. J Biol Chem, 2002 Nov 15. PMID 12171937
  2. Genetic analysis of the dTDP-rhamnose biosynthesis region of the Escherichia coli VW187 (O7:K1) rfb gene cluster: identification of functional homologs of rfbB and rfbA in the rff cluster and correct location of the rffE gene. Marolda CL, et al. J Bacteriol, 1995 Oct. PMID 7559340, Free PMC Article
  3. Structure of the O antigen of Escherichia coli K-12 and the sequence of its rfb gene cluster. Stevenson G, et al. J Bacteriol, 1994 Jul. PMID 7517391, Free PMC Article
  4. Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes. Daniels DL, et al. Science, 1992 Aug 7. PMID 1379743
  5. Genome-wide screening of genes required for swarming motility in Escherichia coli K-12. Inoue T, et al. J Bacteriol, 2007 Feb. PMID 17122336, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables glucose-1-phosphate thymidylyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glucose-1-phosphate thymidylyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables identical protein binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables magnesium ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleotidyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in enterobacterial common antigen biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in extracellular polysaccharide biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in extracellular polysaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in polysaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytosol IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
glucose-1-phosphate thymidylyltransferase 2
NP_418236.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3973608..3974489
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418236.1 glucose-1-phosphate thymidylyltransferase 2 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418236.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A2X1J641
    Conserved Domains (1) summary
    TIGR01207
    Location:2 → 287
    rmlA; glucose-1-phosphate thymidylyltransferase, short form
Nucleotide Protein
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