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rhtB L-homoserine/L-homoserine lactone/L-threonine exporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948316, updated on 11-Apr-2024

Summary

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Gene symbol
rhtB
Gene description
L-homoserine/L-homoserine lactone/L-threonine exporter
Primary source
ASAP:ABE-0012490
Locus tag
b3824
See related
ECOCYC:EG11469
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3818; yigK
Summary
RhtB is a LysE superfamily exporter. [More information is available at EcoGene: EG11469]. RhtB is a probable homoserine and homoserine lactone efflux transporter. [More information is available at EcoCyc: EG11469].
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Genomic context

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Sequence:
NC_000913.3 (4008439..4009059, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ATP-dependent DNA helicase RecQ Neighboring gene L-threonine exporter Neighboring gene lysophospholipase L2 Neighboring gene phosphosugar phosphatase YigL

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The novel transmembrane Escherichia coli proteins involved in the amino acid efflux. Zakataeva NP, et al. FEBS Lett, 1999 Jun 11. PMID 10386596
  2. [Expression of the genes encoding RhtB family proteins depends on global regulator Lrp]. Kutukova EA, et al. Mol Biol (Mosk), 2005 May-Jun. PMID 15981566
  3. The LysE superfamily: topology of the lysine exporter LysE of Corynebacterium glutamicum, a paradyme for a novel superfamily of transmembrane solute translocators. Vrljic M, et al. J Mol Microbiol Biotechnol, 1999 Nov. PMID 10943564
  4. Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes. Daniels DL, et al. Science, 1992 Aug 7. PMID 1379743
  5. New ubiquitous translocators: amino acid export by Corynebacterium glutamicum and Escherichia coli. Eggeling L, et al. Arch Microbiol, 2003 Sep. PMID 12879215

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables homoserine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables homoserine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables homoserine transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables threonine efflux transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables threonine efflux transmembrane transporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in homoserine transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within homoserine transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within homoserine transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within threonine transport IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within threonine transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
L-homoserine/L-homoserine lactone/L-threonine exporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4008439..4009059 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. YP_026265.1 L-homoserine/L-homoserine lactone/L-threonine exporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for YP_026265.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A826P7A3
    Conserved Domains (1) summary
    PRK10520
    Location:1 → 205
    rhtB; homoserine/homoserine lactone efflux protein; Provisional
Nucleotide Protein
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