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pflD putative formate acetyltransferase 2 [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948454, updated on 23-Nov-2023

Summary

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Gene symbol
pflD
Gene description
putative formate acetyltransferase 2
Primary source
ASAP:ABE-0012934
Locus tag
b3951
See related
ECOCYC:EG11910
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3942; yijL
Summary
PflD was identified by sequence similarity as a homolog of pyruvate formate-lyase . [More information is available at EcoCyc: EG11910].
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Genomic context

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Sequence:
NC_000913.3 (4143995..4146292)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative PTS enzyme IIC component FrwC Neighboring gene putative PTS enzyme IIB component FrwB Neighboring gene putative pyruvate formate-lyase 2 activating enzyme PflC Neighboring gene putative PTS enzyme IIB component FrwD Neighboring gene putative DNA-binding transcriptional regulator YijO Neighboring gene phosphoethanolamine transferase EptC

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Pyruvate formate-lyase is not essential for nitrate respiration by Escherichia coli. Kaiser M, et al. FEMS Microbiol Lett, 1994 Apr 1. PMID 8181719
  2. Promoter 7 of the Escherichia coli pfl operon is a major determinant in the anaerobic regulation of expression by ArcA. Drapal N, et al. J Bacteriol, 1995 Sep. PMID 7665524, Free PMC Article
  3. Fumarate reductase mutants of Escherichia coli that lack covalently bound flavin. Blaut M, et al. J Biol Chem, 1989 Aug 15. PMID 2668268
  4. Novel phosphotransferase system genes revealed by bacterial genome analysis--a gene cluster encoding a unique Enzyme I and the proteins of a fructose-like permease system. Reizer J, et al. Microbiology (Reading), 1995 Apr. PMID 7773398
  5. The effect of pfl gene knockout on the metabolism for optically pure D-lactate production by Escherichia coli. Zhu J, et al. Appl Microbiol Biotechnol, 2004 Apr. PMID 14673546

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
putative formate acetyltransferase 2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4143995..4146292
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418386.1 putative formate acetyltransferase 2 [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418386.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A831E261, A0A895NY50
    Conserved Domains (1) summary
    PRK09983
    Location:1 → 765
    pflD; putative formate acetyltransferase 2; Provisional
Nucleotide Protein
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