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murI glutamate racemase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948467, updated on 2-May-2024

Summary

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Gene symbol
murI
Gene description
glutamate racemase
Primary source
ASAP:ABE-0012989
Locus tag
b3967
See related
ECOCYC:EG11204
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
dga; ECK3959; glr; yijA
Summary
murI is an essential gene. [More information is available at EcoGene: EG11204].
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Genomic context

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Sequence:
NC_000913.3 (4165428..4166285)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA-binding transcriptional repressor FabR Neighboring gene DUF1422 domain-containing inner membrane protein YijD Neighboring gene tRNA m(5)U54 methyltransferase Neighboring gene cobalamin outer membrane transporter Neighboring gene 16S ribosomal RNA Neighboring gene tRNA-Glu

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Exploitation of structural and regulatory diversity in glutamate racemases. Lundqvist T, et al. Nature, 2007 Jun 14. PMID 17568739
  2. Isolation of peptide ligands that inhibit glutamate racemase activity from a random phage display library. Kim WC, et al. J Biomol Screen, 2000 Dec. PMID 11598461
  3. Compensation for D-glutamate auxotrophy of Escherichia coli WM335 by D-amino acid aminotransferase gene and regulation of murI expression. Liu L, et al. Biosci Biotechnol Biochem, 1998 Jan. PMID 9501533
  4. Regulation of the glutamate racemase of Escherichia coli investigated by site-directed mutagenesis. Doublet P, et al. Microb Drug Resist, 1996 Spring. PMID 9158721
  5. An Escherichia coli gene in search of a function: phenotypic effects of the gene recently identified as murI. Balikó G, et al. J Bacteriol, 1993 Oct. PMID 8407834, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables glutamate racemase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glutamate racemase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables glutamate racemase activity IEA
Inferred from Electronic Annotation
more info
  
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell wall organization IEA
Inferred from Electronic Annotation
more info
  
involved_in peptidoglycan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in peptidoglycan biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within peptidoglycan biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
glutamate racemase
NP_418402.2

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4165428..4166285
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418402.2 glutamate racemase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418402.2

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A1X3J9Y8
    Conserved Domains (1) summary
    PRK00865
    Location:17 → 281
    PRK00865; glutamate racemase; Provisional
Nucleotide Protein
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