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aceB malate synthase A [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948512, updated on 4-Apr-2024

Summary

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Gene symbol
aceB
Gene description
malate synthase A
Primary source
ASAP:ABE-0013125
Locus tag
b4014
See related
ECOCYC:EG10023
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4006; mas
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Genomic context

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Sequence:
NC_000913.3 (4215478..4217079)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene peptidyl-lysine N-acetyltransferase YjaB Neighboring gene homoserine O-succinyltransferase Neighboring gene isocitrate lyase Neighboring gene ncRNA Neighboring gene isocitrate dehydrogenase kinase/phosphatase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Phenotypic suppression of phosphofructokinase mutations in Escherichia coli by constitutive expression of the glyoxylate shunt. Vinopal RT, et al. J Bacteriol, 1974 Jun. PMID 4275310, Free PMC Article
  2. Nucleotide sequence of the aceB gene encoding malate synthase A in Escherichia coli. Byrne C, et al. Nucleic Acids Res, 1988 Oct 11. PMID 3050899, Free PMC Article
  3. Atomic resolution structures of Escherichia coli and Bacillus anthracis malate synthase A: comparison with isoform G and implications for structure-based drug discovery. Lohman JR, et al. Protein Sci, 2008 Nov. PMID 18714089, Free PMC Article
  4. The binding site of the IclR repressor protein overlaps the promoter of aceBAK. Pan B, et al. J Bacteriol, 1996 Jul. PMID 8682810, Free PMC Article
  5. Elevated levels of glyoxylate shunt enzymes in Escherichia coli strains constitutive for fatty acid degradation. Maloy SR, et al. J Bacteriol, 1980 Aug. PMID 7009561, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
  
enables malate synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables malate synthase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables malate synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in glyoxylate cycle IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within glyoxylate cycle IC
Inferred by Curator
more info
 PubMed 
involved_in glyoxylate cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
malate synthase A
NP_418438.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4215478..4217079
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418438.1 malate synthase A [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418438.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7EEN6, A0A8S7NN01
    Conserved Domains (1) summary
    PRK09255
    Location:4 → 533
    PRK09255; malate synthase; Validated
Nucleotide Protein
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