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phnO aminoalkylphosphonate N-acetyltransferase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948599, updated on 2-May-2024

Summary

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Gene symbol
phnO
Gene description
aminoalkylphosphonate N-acetyltransferase
Primary source
ASAP:ABE-0013415
Locus tag
b4093
See related
ECOCYC:EG10724
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4086
Summary
Phosphonate utilization is cryptic in K-12. [More information is available at EcoGene: EG10724]. phnO is part of an operon involved in utilization of phosphonate as a source of phosphorus . [More information is available at EcoCyc: EG10724].
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Genomic context

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Sequence:
NC_000913.3 (4315104..4315538, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein YjdP Neighboring gene 5-phospho-alpha-D-ribosyl 1,2-cyclic phosphate phosphodiesterase Neighboring gene ribose 1,5-bisphosphate phosphokinase Neighboring gene RPnTP hydrolase Neighboring gene methylphosphonate degradation complex subunit PhnL Neighboring gene carbon-phosphorus lyase subunit PhnK Neighboring gene carbon-phosphorus lyase core complex subunit PhnJ

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Catabolism and detoxification of 1-aminoalkylphosphonic acids: N-acetylation by the phnO gene product. Hove-Jensen B, et al. PLoS One, 2012. PMID 23056305, Free PMC Article
  2. Identification of Novel Protein Lysine Acetyltransferases in Escherichia coli. Christensen DG, et al. mBio, 2018 Oct 23. PMID 30352934, Free PMC Article
  3. Accumulation of intermediates of the carbon-phosphorus lyase pathway for phosphonate degradation in phn mutants of Escherichia coli. Hove-Jensen B, et al. J Bacteriol, 2010 Jan. PMID 19854894, Free PMC Article
  4. Functional annotation and kinetic characterization of PhnO from Salmonella enterica. Errey JC, et al. Biochemistry, 2006 Mar 7. PMID 16503658, Free PMC Article
  5. Involvement of the Escherichia coli phn (psiD) gene cluster in assimilation of phosphorus in the form of phosphonates, phosphite, Pi esters, and Pi. Metcalf WW, et al. J Bacteriol, 1991 Jan. PMID 1846145, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables N-acetyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables acyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
Inferred from Electronic Annotation
more info
  
enables peptide-lysine-N-acetyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables peptide-lysine-N-acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within aminophosphonate metabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
aminoalkylphosphonate N-acetyltransferase
NP_418517.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4315104..4315538 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418517.1 aminoalkylphosphonate N-acetyltransferase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418517.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S0G2V6
    Conserved Domains (1) summary
    PRK10146
    Location:1 → 144
    PRK10146; aminoalkylphosphonate N-acetyltransferase
Nucleotide Protein
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