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phnI carbon-phosphorus lyase core complex subunit PhnI [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948605, updated on 4-Feb-2024

Summary

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Gene symbol
phnI
Gene description
carbon-phosphorus lyase core complex subunit PhnI
Primary source
ASAP:ABE-0013428
Locus tag
b4099
See related
ECOCYC:EG10718
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4092
Summary
Phosphonate utilization is cryptic in K-12. [More information is available at EcoGene: EG10718]. PhnI is required for the use of phosphonate as a phosphorus source. phnI is part of an operon that is phosphate starvation inducible and required for use of phosphonate and phosphite as phosphorus sources . phnI is required for use of phosphonates but not for uptake . [More information is available at EcoCyc: EG10718].
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Genomic context

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Sequence:
NC_000913.3 (4319599..4320663, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene RPnTP hydrolase Neighboring gene methylphosphonate degradation complex subunit PhnL Neighboring gene carbon-phosphorus lyase subunit PhnK Neighboring gene carbon-phosphorus lyase core complex subunit PhnJ Neighboring gene carbon-phosphorus lyase core complex subunit PhnH Neighboring gene carbon-phosphorus lyase core complex subunit PhnG Neighboring gene putative transcriptional regulator PhnF

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structural insights into the bacterial carbon-phosphorus lyase machinery. Seweryn P, et al. Nature, 2015 Sep 3. PMID 26280334, Free PMC Article
  2. Structures of the Carbon-Phosphorus Lyase Complex Reveal the Binding Mode of the NBD-like PhnK. Yang K, et al. Structure, 2016 Jan 5. PMID 26724995, Free PMC Article
  3. Subunit Interactions within the Carbon-Phosphorus Lyase Complex from Escherichia coli. Ren Z, et al. Biochemistry, 2015 Jun 2. PMID 25954983, Free PMC Article
  4. Five phosphonate operon gene products as components of a multi-subunit complex of the carbon-phosphorus lyase pathway. Jochimsen B, et al. Proc Natl Acad Sci U S A, 2011 Jul 12. PMID 21705661, Free PMC Article
  5. Mapping and molecular cloning of the phn (psiD) locus for phosphonate utilization in Escherichia coli. Wanner BL, et al. J Bacteriol, 1990 Mar. PMID 2155195, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within organic phosphonate catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in organic phosphonate metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in organic phosphonate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in organic phosphonate transport IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex IPI
Inferred from Physical Interaction
more info
 PubMed 
part_of carbon phosphorus lyase complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of carbon phosphorus lyase complex IPI
Inferred from Physical Interaction
more info
 PubMed 

General protein information

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Preferred Names
carbon-phosphorus lyase core complex subunit PhnI
NP_418523.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4319599..4320663 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418523.1 carbon-phosphorus lyase core complex subunit PhnI [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418523.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5B9AMT4, A0A827Y382
    Conserved Domains (1) summary
    COG3626
    Location:1 → 354
    PhnI; Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI [Inorganic ion transport and metabolism]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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