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yjeH L-methionine/branched chain amino acid exporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948656, updated on 11-Apr-2024

Summary

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Gene symbol
yjeH
Gene description
L-methionine/branched chain amino acid exporter
Primary source
ASAP:ABE-0013559
Locus tag
b4141
See related
ECOCYC:G7833
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4135
Summary
A yjeH mutant of Salmonella has reduced ceftriaxone resistance and altered OM protein levels (Hu, 2007). [More information is available at EcoGene: EG12470]. YjeH is an uncharacterized member of the APC superfamily of amino acid transporters . [More information is available at EcoCyc: G7833].
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Genomic context

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Sequence:
NC_000913.3 (4369156..4370412, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene aspartate ammonia-lyase Neighboring gene protein FxsA Neighboring gene cochaperonin GroES Neighboring gene chaperonin GroEL

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. YjeH Is a Novel Exporter of l-Methionine and Branched-Chain Amino Acids in Escherichia coli. Liu Q, et al. Appl Environ Microbiol, 2015 Nov. PMID 26319875, Free PMC Article
  2. A proteomic approach to study Salmonella enterica serovar Typhimurium putative transporter YjeH associated with ceftriaxone resistance. Hu WS, et al. Biochem Biophys Res Commun, 2007 Sep 28. PMID 17669360
  3. Analysis of the Escherichia coli genome VI: DNA sequence of the region from 92.8 through 100 minutes. Burland V, et al. Nucleic Acids Res, 1995 Jun 25. PMID 7610040, Free PMC Article
  4. The amino acid/polyamine/organocation (APC) superfamily of transporters specific for amino acids, polyamines and organocations. Jack DL, et al. Microbiology (Reading), 2000 Aug. PMID 10931886
  5. Experimentally constrained topology models for 51,208 bacterial inner membrane proteins. Granseth E, et al. J Mol Biol, 2005 Sep 23. PMID 16120447

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables L-methionine secondary active transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables antiporter activity IEA
Inferred from Electronic Annotation
more info
  
enables neutral L-amino acid secondary active transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within L-leucine transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within L-valine transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cellular response to amino acid stimulus IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within isoleucine transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within methionine transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISM
Inferred from Sequence Model
more info
 PubMed 
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 

General protein information

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Preferred Names
L-methionine/branched chain amino acid exporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4369156..4370412 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418565.1 L-methionine/branched chain amino acid exporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418565.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A8S7R6P5
    Conserved Domains (1) summary
    PRK11021
    Location:8 → 411
    PRK11021; putative transporter; Provisional
Nucleotide Protein
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