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nnr NAD(P)HX epimerase/NAD(P)HX dehydratase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948685, updated on 2-May-2024

Summary

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Gene symbol
nnr
Gene description
NAD(P)HX epimerase/NAD(P)HX dehydratase
Primary source
ASAP:ABE-0013644
Locus tag
b4167
See related
ECOCYC:EG11758
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4163; yjeF
Summary
Insertions in yjeF indicate this gene is likely to be non-essential. [More information is available at EcoGene: EG11758].
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Genomic context

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Sequence:
NC_000913.3 (4394066..4395613)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Gly Neighboring gene uncharacterized protein YjeV Neighboring gene epoxyqueuosine reductase Neighboring gene N(6)-L-threonylcarbamoyladenine synthase, TsaE subunit Neighboring gene N-acetylmuramoyl-L-alanine amidase B Neighboring gene DNA mismatch repair protein MutL Neighboring gene tRNA dimethylallyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Extremely conserved ATP- or ADP-dependent enzymatic system for nicotinamide nucleotide repair. Marbaix AY, et al. J Biol Chem, 2011 Dec 2. PMID 21994945, Free PMC Article
  2. The mutL repair gene of Escherichia coli K-12 forms a superoperon with a gene encoding a new cell-wall amidase. Tsui HC, et al. Mol Microbiol, 1994 Jan. PMID 7511774
  3. Transcription of the mutL repair, miaA tRNA modification, hfq pleiotropic regulator, and hflA region protease genes of Escherichia coli K-12 from clustered Esigma32-specific promoters during heat shock. Tsui HC, et al. J Bacteriol, 1996 Oct. PMID 8824618, Free PMC Article
  4. Characterization of broadly pleiotropic phenotypes caused by an hfq insertion mutation in Escherichia coli K-12. Tsui HC, et al. Mol Microbiol, 1994 Jul. PMID 7984093
  5. Transcriptional patterns of the mutL-miaA superoperon of Escherichia coli K-12 suggest a model for posttranscriptional regulation. Tsui HC, et al. Biochimie, 1994. PMID 7748952

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables ADP-dependent NAD(P)H-hydrate dehydratase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ADP-dependent NAD(P)H-hydrate dehydratase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ADP-dependent NAD(P)H-hydrate dehydratase activity IEA
Inferred from Electronic Annotation
more info
  
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables NADHX epimerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables NADHX epimerase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables NADHX epimerase activity IEA
Inferred from Electronic Annotation
more info
  
enables NADPHX epimerase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables NADPHX epimerase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables NADPHX epimerase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydro-lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in metabolite repair IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within metabolite repair IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in nicotinamide nucleotide metabolic process IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
NAD(P)HX epimerase/NAD(P)HX dehydratase
NP_418588.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4394066..4395613
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418588.1 NAD(P)HX epimerase/NAD(P)HX dehydratase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418588.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A827YA93
    Conserved Domains (1) summary
    PRK10565
    Location:1 → 508
    PRK10565; putative carbohydrate kinase; Provisional
Nucleotide Protein
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