purA adenylosuccinate synthetase [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Gene symbol: purA
Gene description: adenylosuccinate synthetase
Primary source: ASAP:ABE-0013672
Locus tag: b4177
See related: ECOCYC:EG10790
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: adeK; ECK4173
Summary: Adenylosuccinate synthetase catalyzes the first committed step toward the de novo synthesis of AMP. [More information is available at EcoCyc: EG10790].
NEW: Try the new Gene table
Try the new Transcript table

NC_000913.3 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables adenylosuccinate synthase activity	IBA Inferred from Biological aspect of Ancestor more info
enables adenylosuccinate synthase activity	IDA Inferred from Direct Assay more info	PubMed
enables adenylosuccinate synthase activity	IEA Inferred from Electronic Annotation more info
enables guanosine tetraphosphate binding	IDA Inferred from Direct Assay more info	PubMed
enables ligase activity	IEA Inferred from Electronic Annotation more info
enables magnesium ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in 'de novo' AMP biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in 'de novo' AMP biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within DNA damage response	IEP Inferred from Expression Pattern more info	PubMed
involved_in IMP metabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within adenosine biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within nucleobase-containing small molecule interconversion	IDA Inferred from Direct Assay more info	PubMed
involved_in purine nucleotide biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within purine nucleotide biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	HDA more info	PubMed
located_in cytosol	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	HDA more info	PubMed

NP_418598.1

NEW Try the new Transcript table

The following sections contain reference sequences that belong to a specific genome build. Explain