nrdG anaerobic ribonucleoside-triphosphate reductase activating protein [Escherichia coli str. K-12 substr. MG1655] - Gene

Summary

Gene symbol: nrdG
Gene description: anaerobic ribonucleoside-triphosphate reductase activating protein
Primary source: ASAP:ABE-0013860
Locus tag: b4237
See related: ECOCYC:G812
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage: Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as: ECK4232; yjgE
Summary: FNR regulon. [More information is available at EcoGene: EG12523]. An nrdG null mutant does not grow under entirely anaerobic conditions, but grows under aerobic or microaerophilic conditions due to the activity of NrdA and/or NrdB . [More information is available at EcoCyc: G812].
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NC_000913.3 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables 4 iron, 4 sulfur cluster binding	IDA Inferred from Direct Assay more info	PubMed
enables 4 iron, 4 sulfur cluster binding	IEA Inferred from Electronic Annotation more info
enables [formate-C-acetyltransferase]-activating enzyme activity	IEA Inferred from Electronic Annotation more info
enables iron-sulfur cluster binding	IDA Inferred from Direct Assay more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
contributes_to ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IBA Inferred from Biological aspect of Ancestor more info
contributes_to ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	IMP Inferred from Mutant Phenotype more info	PubMed

Process	Evidence Code	Pubs
involved_in 2'-deoxyribonucleotide biosynthetic process	NAS Non-traceable Author Statement more info	PubMed
acts_upstream_of_or_within nucleobase-containing small molecule interconversion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in nucleobase-containing small molecule interconversion	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
part_of anaerobic ribonucleoside-triphosphate reductase complex	IMP Inferred from Mutant Phenotype more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

Preferred Names: anaerobic ribonucleoside-triphosphate reductase activating protein

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