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gntP fructuronate transporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948848, updated on 11-Apr-2024

Summary

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Gene symbol
gntP
Gene description
fructuronate transporter
Primary source
ASAP:ABE-0014161
Locus tag
b4321
See related
ECOCYC:EG12563
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4312; yjiB
Summary
Induced by fructuronate, but not gluconate; induced by glucuronate via its conversion to fructuronate. [More information is available at EcoGene: EG12563]. GntP is a member of the GntP family transporters and is homologous to the Escherichia coli GntT and GntU gluconate transporters. [More information is available at EcoCyc: EG12563].
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Genomic context

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Sequence:
NC_000913.3 (4549953..4551296, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene type 1 fimbriae minor subunit FimG Neighboring gene type 1 fimbriae D-mannose specific adhesin Neighboring gene D-mannonate dehydratase Neighboring gene D-mannonate oxidoreductase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. GntP is the Escherichia coli Fructuronic acid transporter and belongs to the UxuR regulon. Bates Utz C, et al. J Bacteriol, 2004 Nov. PMID 15516583, Free PMC Article
  2. The gntP gene of Escherichia coli involved in gluconate uptake. Klemm P, et al. J Bacteriol, 1996 Jan. PMID 8550444, Free PMC Article
  3. Regulation of hexuronate system genes in Escherichia coli K-12: multiple regulation of the uxu operon by exuR and uxuR gene products. Robert-Baudouy J, et al. J Bacteriol, 1981 Jan. PMID 7007313, Free PMC Article
  4. Target prediction for small, noncoding RNAs in bacteria. Tjaden B, et al. Nucleic Acids Res, 2006. PMID 16717284, Free PMC Article
  5. Domain structure and pore loops in the 2-hydroxycarboxylate transporter family. Lolkema JS. J Mol Microbiol Biotechnol, 2006. PMID 17114896

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. induced by fructuronate and is a new member of the UxuR regulon, and required for growth on fructuronate
    Title: GntP is the Escherichia coli Fructuronic acid transporter and belongs to the UxuR regulon.
Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables carbohydrate:proton symporter activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables gluconate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables gluconate transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables gluconate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in D-gluconate catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in D-gluconate metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in carbohydrate transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in gluconate transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within gluconate transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in gluconate transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in organic substance transport IEA
Inferred from Electronic Annotation
more info
  
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
fructuronate transporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4549953..4551296 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418741.1 fructuronate transporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418741.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A3L5GYQ5, A0A5B9AAQ9
    Conserved Domains (1) summary
    PRK10034
    Location:1 → 447
    PRK10034; gluconate transporter GntP
Nucleotide Protein
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