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fhuF ferric-siderophore reductase FhuF [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948891, updated on 4-Apr-2024

Summary

Gene symbol
fhuF
Gene description
ferric-siderophore reductase FhuF
Primary source
ASAP:ABE-0014326
Locus tag
b4367
See related
ECOCYC:G7949
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4357; yjjS
Summary
CsdB (SufS) and SufD are required to insert an iron-sulfur cluster into FhuF. [More information is available at EcoGene: EG12595]. FhuF is likely to act in iron reduction during utilization of a ferrioxamine B iron source . [More information is available at EcoCyc: G7949].
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Genomic context

Sequence:
NC_000913.3 (4604875..4605663, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative succinate exporter YjjB Neighboring gene putative succinate exporter YjjP Neighboring gene DNA-binding transcriptional repressor YjjQ Neighboring gene DNA-binding transcriptional regulator BglJ Neighboring gene DUF1435 domain-containing protein YjjZ Neighboring gene tRNA-Leu

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables 2 iron, 2 sulfur cluster binding IDA
Inferred from Direct Assay
more info
PubMed 
enables 2 iron, 2 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables catalytic activity IEA
Inferred from Electronic Annotation
more info
 
enables ferric-chelate reductase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables iron-sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity, acting on metal ions IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ferric-siderophore reductase FhuF

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4604875..4605663 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418787.1 ferric-siderophore reductase FhuF [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418787.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0AA90FPV4
    Conserved Domains (1) summary
    PRK10647
    Location:1262
    PRK10647; ferric iron reductase involved in ferric hydroximate transport; Provisional