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serB phosphoserine phosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948913, updated on 2-May-2024

Summary

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Gene symbol
serB
Gene description
phosphoserine phosphatase
Primary source
ASAP:ABE-0014393
Locus tag
b4388
See related
ECOCYC:EG10945
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4380
Summary
HAD superfamily. [More information is available at EcoGene: EG10945]. Phosphoserine phosphatase catalyzes the last step in serine biosynthesis. [More information is available at EcoCyc: EG10945].
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Genomic context

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Sequence:
NC_000913.3 (4624895..4625863)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene lipoate--protein ligase A Neighboring gene putative inner membrane protein Smp Neighboring gene DNA recombination protein Neighboring gene DNA-binding transcriptional repressor/NMN adenylyltransferase NadR

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. THE PATHWAY AND CONTROL OF SERINE BIOSYNTHESIS IN ESCHERICHIA COLI. PIZER LI. J Biol Chem, 1963 Dec. PMID 14086727
  2. Construction and analysis of plasmids containing the Escherichia coli serB gene. Garnant MK, et al. Mol Gen Genet, 1984. PMID 6318053
  3. DNA sequence and characterization of the Escherichia coli serB gene. Neuwald AF, et al. Nucleic Acids Res, 1985 Oct 11. PMID 2997734, Free PMC Article
  4. BIOSYNTHESIS OF SERINE IN ESCHERICHIA COLI AND SALMONELLA TYPHIMURIUM. UMBARGER HE, et al. J Bacteriol, 1963 Jun. PMID 14047241, Free PMC Article
  5. Mutational analysis of the Escherichia coli serB promoter region reveals transcriptional linkage to a downstream gene. Neuwald AF, et al. Gene, 1992 Oct 12. PMID 1327967

See all (19) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables L-phosphoserine phosphatase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables L-phosphoserine phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables L-phosphoserine phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables magnesium ion binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables magnesium ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-serine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within L-serine biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in L-serine biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in L-serine biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within amino acid biosynthetic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in dephosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
phosphoserine phosphatase
NP_418805.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4624895..4625863
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418805.1 phosphoserine phosphatase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418805.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A377DYT7, A0A8S7EK95
    Conserved Domains (1) summary
    PRK11133
    Location:1 → 322
    serB; phosphoserine phosphatase; Provisional
Nucleotide Protein
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