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hycD formate hydrogenlyase subunit HycD [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948994, updated on 4-Apr-2024

Summary

Gene symbol
hycD
Gene description
formate hydrogenlyase subunit HycD
Primary source
ASAP:ABE-0008946
Locus tag
b2722
See related
ECOCYC:EG10477
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2717; hevD
Summary
FhlA regulon. [More information is available at EcoGene: EG10477]. HycD encodes an extremely hydrophobic protein with 8 predicted transmembrane domains. [More information is available at EcoCyc: EG10477].
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Genomic context

Sequence:
NC_000913.3 (2846489..2847412, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene formate hydrogenlyase subunit HycG Neighboring gene formate hydrogenlyase subunit HycF Neighboring gene formate hydrogenlyase subunit HycE Neighboring gene formate hydrogenlyase subunit HycC Neighboring gene formate hydrogenlyase subunit HycB Neighboring gene regulator of the transcriptional regulator FhlA

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in anaerobic electron transport chain IDA
Inferred from Direct Assay
more info
PubMed 
involved_in anaerobic respiration IDA
Inferred from Direct Assay
more info
PubMed 
involved_in formate oxidation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in glucose catabolic process IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
part_of formate dehydrogenase complex IPI
Inferred from Physical Interaction
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane RCA
inferred from Reviewed Computational Analysis
more info
PubMed 

General protein information

Preferred Names
formate hydrogenlyase subunit HycD
NP_417202.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2846489..2847412 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417202.1 formate hydrogenlyase subunit HycD [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417202.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7H9QLV0
    Conserved Domains (1) summary
    COG0650
    Location:1306
    HyfC; Formate hydrogenlyase subunit 4 [Energy production and conversion]