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citT citrate:succinate antiporter [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 949070, updated on 23-Nov-2023

Summary

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Gene symbol
citT
Gene description
citrate:succinate antiporter
Primary source
ASAP:ABE-0002110
Locus tag
b0612
See related
ECOCYC:G6338
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK0605; ybdS
Summary
CitT is an integral membrane protein with 12 TM regions. [More information is available at EcoGene: EG13538]. CitT is a probable citrate/succinate antiporter, responsible for the uptake of citrate. [More information is available at EcoCyc: G6338].
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Genomic context

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Sequence:
NC_000913.3 (645117..646580, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene nucleoside diphosphate kinase regulator Neighboring gene RNase I Neighboring gene triphosphoribosyl-dephospho-CoA synthase Neighboring gene apo-citrate lyase phosphoribosyl-dephospho-CoA transferase Neighboring gene citrate lyase alpha subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning and DNA sequence of a plasmid-determined citrate utilization system in Escherichia coli. Sasatsu M, et al. J Bacteriol, 1985 Dec. PMID 2999088, Free PMC Article
  2. CORRELATION OF CITRATE UTILIZATION BY MEMBERS OF THE COLON-AEROGENES GROUP WITH OTHER DIFFERENTIAL CHARACTERISTICS AND WITH HABITAT. Koser SA. J Bacteriol, 1924 Jan. PMID 16559027, Free PMC Article
  3. Why a co-substrate is required for anaerobic growth of Escherichia coli on citrate. Lütgens M, et al. J Gen Microbiol, 1980 Jul. PMID 6997437
  4. SOS response induction by beta-lactams and bacterial defense against antibiotic lethality. Miller C, et al. Science, 2004 Sep 10. PMID 15308764
  5. The Escherichia coli citrate carrier CitT: a member of a novel eubacterial transporter family related to the 2-oxoglutarate/malate translocator from spinach chloroplasts. Pos KM, et al. J Bacteriol, 1998 Aug. PMID 9696764, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables antiporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
citrate:succinate antiporter

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    645117..646580 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_415145.1 citrate:succinate antiporter [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_415145.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A7A7AW06
    Conserved Domains (1) summary
    pfam00939
    Location:5 → 486
    Na_sulph_symp; Sodium:sulfate symporter transmembrane region
Nucleotide Protein
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