5jw5

X-ray diffraction
1.9Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-213815 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
MEDI8852 Heavy chain Chains: A, H
Molecule details ›
Chains: A, H
Length: 227 amino acids
Theoretical weight: 24.46 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
MEDI8852 Light chain Chains: B, L
Molecule details ›
Chains: B, L
Length: 210 amino acids
Theoretical weight: 22.91 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P212121
Unit cell:
a: 65.22Å b: 109.92Å c: 139.89Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.187 0.217
Expression system: Homo sapiens