Abstract
We report the case of a young man who apparently suffered successive episodes of meningitis and cerebral abscess over a 1-month period, both of which were diagnosed by two different molecular approaches; PCR for Neisseria meningitidis IS1106 from CSF and 16S rRNA gene sequencing on a specimen of brain pus. In each case, cultures were negative due to prior antibiotic therapy.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Brain Abscess / diagnosis
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Brain Abscess / genetics
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Brain Abscess / microbiology*
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DNA, Bacterial*
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Humans
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Male
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Meningitis, Meningococcal / diagnosis
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Meningitis, Meningococcal / genetics
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Neisseria meningitidis / genetics
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Neisseria meningitidis / isolation & purification
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RNA, Ribosomal, 16S / genetics*
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Sequence Analysis, DNA / methods
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Species Specificity
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Suppuration / diagnosis
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Suppuration / microbiology
Substances
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DNA, Bacterial
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RNA, Ribosomal, 16S