Mapping of the alpha-1,6-fucosyltransferase gene, FUT8, to human chromosome 14q24.3

Cytogenet Cell Genet. 1999;84(1-2):58-60. doi: 10.1159/000015215.

Abstract

Alpha-1,6-Fucosyltransferase (alpha1,6FucT) is involved in the biosynthesis of asparagine-linked glycoprotein oligosaccharides. In this study, we isolated a genomic clone for the human alpha1,6FucT gene (FUT8) and mapped it by fluorescence in situ hybridization to chromosome 14q24.3. This study suggests a distinct localization of FUT8 from genes for other human fucosyltransferases reported to date.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosome Mapping
  • Chromosomes, Human, Pair 14 / genetics*
  • Cloning, Molecular
  • DNA, Complementary / genetics
  • Exons
  • Fucosyltransferases / genetics*
  • Humans
  • In Situ Hybridization, Fluorescence
  • Molecular Sequence Data
  • Restriction Mapping

Substances

  • DNA, Complementary
  • Fucosyltransferases
  • galactoside 3-fucosyltransferase
  • Glycoprotein 6-alpha-L-fucosyltransferase

Associated data

  • GENBANK/AF038280
  • GENBANK/AF038281
  • GENBANK/AH005745