Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas

Nat Genet. 1999 Sep;23(1):18-20. doi: 10.1038/12615.

Authors

D Cappellen¹, C De Oliveira, D Ricol, S de Medina, J Bourdin, X Sastre-Garau, D Chopin, J P Thiery, F Radvanyi

Affiliation

¹ Laboratoire de Morphogenèse Cellulaire et Progression Tumorale, UMR 144, Centre National de la Recherche Scientifique, Institut Curie, Section de Recherche, 26 rue d'Ulm, 75248 Paris Cedex 05, France.

PMID: 10471491
DOI: 10.1038/12615

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Sequence
Cervix Uteri / metabolism
Epithelium / metabolism
Female
Gene Expression Regulation, Neoplastic
Humans
Molecular Sequence Data
Mutation*
Mutation, Missense
Point Mutation
Protein-Tyrosine Kinases*
Receptor, Fibroblast Growth Factor, Type 3
Receptors, Fibroblast Growth Factor / genetics*
Translocation, Genetic
Urinary Bladder / metabolism
Urinary Bladder Neoplasms / genetics*
Uterine Cervical Neoplasms / genetics*

Substances

Receptors, Fibroblast Growth Factor
FGFR3 protein, human
Protein-Tyrosine Kinases
Receptor, Fibroblast Growth Factor, Type 3